Ignite Creation Date:
2024-05-06 @ 8:04 PM
Last Modification Date:
2024-10-26 @ 3:20 PM
Study NCT ID:
NCT06243497
Status:
RECRUITING
Last Update Posted:
2024-02-06
First Post:
2023-09-26
Brief Title:
Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment
Sponsor:
Zhongshan Ophthalmic Center Sun Yat-sen University
Organization:
Zhongshan Ophthalmic Center Sun Yat-sen University
Study Overview
Official Title:
Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment
Status:
RECRUITING
Status Verified Date:
2023-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Glaucoma is the leading cause of irreversible vision loss in people aged 50 years and older worldwide second only to cataracts Ultrasound Cyclo Plasty was first proposed as a new minimally invasive technique in the 1980 s In recent years many clinical studies at home and abroad have confirmed the effectiveness safety and repeatability of UCP The ciliary body is the target organ of UCP and the range and accuracy of intraoperative destruction of the ciliary body are the key factors affecting the success or failure of the operation The production of aqueous humor is closely related to the ciliary body The dynamic balance of its production and discharge can affect IOP and its content can directly reflect the intraocular environment Besidestears are easy to collect and can be used for follow-up Previous studies have shown that various proteins in aqueous humor or tear can provide a basis for the pathophysiological changes of glaucoma and can also be a potential biomarker for predicting the success of anti-glaucoma surgery
At present UCP related research focuses on its effectiveness and safety mainly reflected in three aspects postoperative intraocular pressure number of anti-glaucoma drugs and complications and lack of relevant indicators that directly reflect postoperative intraocular environment changes The purpose of this study was to reveal the changes of cytokines in aqueous humor after UCP in patients with primary glaucoma to analyze the possible causes of these factors and to speculate the effect of their interaction on the surgical effect in order to increase the predictability of UCP procedure
At present UCP related research focuses on its effectiveness and safety mainly reflected in three aspects postoperative intraocular pressure number of anti-glaucoma drugs and complications and lack of relevant indicators that directly reflect postoperative intraocular environment changes The purpose of this study was to reveal the changes of cytokines in aqueous humor after UCP in patients with primary glaucoma to analyze the possible causes of these factors and to speculate the effect of their interaction on the surgical effect in order to increase the predictability of UCP procedure
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None