Ignite Creation Date:
2024-05-06 @ 8:03 PM
Last Modification Date:
2024-10-26 @ 3:19 PM
Study NCT ID:
NCT06239246
Status:
RECRUITING
Last Update Posted:
2024-02-02
First Post:
2023-12-25
Brief Title:
Association Between Cardiovascular Diseases and Mental Illness
Sponsor:
Ningbo No 1 Hospital
Organization:
Ningbo No 1 Hospital
Study Overview
Official Title:
Analyzing the Association Between Cardiovascular Diseases and Mental Illness Considering Environmental Risk Factors
Status:
RECRUITING
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Cardiovascular diseases CVD are important public health concerns around the world and closely associated with the development and progression of mental illness which in turn increases the risk of developing cardiovascular diseases This study aimed 1 to explore the known or unknown protective and risk factors underlying this comorbidity using questionnaires 2 to study the biomarkers body fluid imaging of the participants and to find the influence on the relationship between CVD and mental health 3 to identify high-risk populations for mental disorders in CVD patients and to establish prediction models 4 to establish a specialized medical database
Detailed Description:
Patients with depression and cardiovascular comorbidities have a worse prognosis a sharply reduced quality of life and a much higher incidence of fatal CVD events such as acute infarction than patients with a single disease However due to the variety of potential causative factors and clinical manifestations population variability long duration of the disease as well as neurological disorders of the exact causative mechanism still unclear the psychological assessment among patients with cardiovascular diseases is remarkably inadequate studied
In this study two cohorts are established that include 2000 hospitalized patients and 5000 of the entire population All individuals are screened for depression and anxiety Those who score positive will be advised to enroll in this study Patients are then randomized to receive collaborative care involving the patient the patients primary care physician cardiologist and nurse case manager or usual care is defined for each patient Whole blood and serum samples are obtained from all patients which will be measured for a panel of metabolic and inflammatory indicators Patients in both cohorts will be monitored for depression severity and duration at 6 and 12 months after enrollment A statistical technique is applied to determine the effect size of potential risk factors
In this study two cohorts are established that include 2000 hospitalized patients and 5000 of the entire population All individuals are screened for depression and anxiety Those who score positive will be advised to enroll in this study Patients are then randomized to receive collaborative care involving the patient the patients primary care physician cardiologist and nurse case manager or usual care is defined for each patient Whole blood and serum samples are obtained from all patients which will be measured for a panel of metabolic and inflammatory indicators Patients in both cohorts will be monitored for depression severity and duration at 6 and 12 months after enrollment A statistical technique is applied to determine the effect size of potential risk factors
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None