Ignite Creation Date:
2024-05-06 @ 7:58 PM
Last Modification Date:
2024-10-26 @ 3:17 PM
Study NCT ID:
NCT06203301
Status:
RECRUITING
Last Update Posted:
2024-01-12
First Post:
2023-12-18
Brief Title:
The Relationships of Resistance Exercise Walking Myokine Secretion Sarcopenia Muscle Loss Quality of Life and Predictors in Cancer Patients Receiving Chemoradiotheray
Sponsor:
Taipei Medical University
Organization:
Taipei Medical University
Study Overview
Official Title:
The Relationships of Resistance Exercise Walking Myokine Secretion Sarcopenia Muscle Loss Quality of Life and Predictors in Cancer Patients Receiving Chemoradiotheray
Status:
RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Cancer is the first most common cause of death in Taiwan The application of surgery and chemoradiotherapy are used for treatment of patients with cancer However loss of muscle mass low muscle strength low physical performance and sarcopenia are induced during chemoradiotherapy consequently increased the risk of hematological toxicity and nonhematological toxicity decreased quality of life and survival rate It was reported that skeletal muscle can secretion of myokines which contribute to muscle synthesis growth repair or atrophy Investigators suggest that detection of blood concentration of myokines and sarcopenia-related predictors can early detection potential individuals who are susceptibility to sarcopenia in cervical cancer patients receiving chemoradiotherapy Also resistance exercise was demonstrated to improve muscle mass muscle strength physical performance and sarcopenia Investigators suggest that resistance exercise can prevent cervical cancer patients from sarcopenia and improve quality of life through regulation the concentration of myokines However there was no study has been investigated their relationships Therefore investigators will conduct a randomized controlled trial study to estimate 1 the effect of resistance exercise walking on regulation myokine secretion improving skeletal muscle mass muscle strength physical performance sarcopenia and quality of life in cancer receiving chemoradiotherapy 2 myokine level muscle mass muscle strength physical performance and sarcopenia incidence in cancer patients before and after receiving chemoradiotherapy
Detailed Description:
Cancer is the first most common cause of death in Taiwan The application of surgery and chemoradiotherapy are used for treatment of patients with cancer However loss of muscle mass low muscle strength low physical performance and sarcopenia are induced during chemoradiotherapy consequently increased the risk of hematological toxicity and nonhematological toxicity decreased quality of life and survival rate It was reported that skeletal muscle can secretion of myokines which contribute to muscle synthesis growth repair or atrophy Investigators suggest that detection of blood concentration of myokines and sarcopenia-related predictors can early detection potential individuals who are susceptibility to sarcopenia in cervical cancer patients receiving chemoradiotherapy Also resistance exercise was demonstrated to improve muscle mass muscle strength physical performance and sarcopenia Investigators suggest that resistance exercise can prevent cervical cancer patients from sarcopenia and improve quality of life through regulation the concentration of myokines However there was no study has been investigated their relationships Therefore investigators will conduct a randomized controlled trial study to estimate 1 the effect of resistance exercise walking on regulation myokine secretion improving skeletal muscle mass muscle strength physical performance sarcopenia and quality of life in cancer receiving chemoradiotherapy 2 myokine level muscle mass muscle strength physical performance and sarcopenia incidence in cancer patients before and after receiving chemoradiotherapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None