Ignite Creation Date:
2025-12-24 @ 7:32 PM
Ignite Modification Date:
2025-12-30 @ 3:36 AM
Study NCT ID:
NCT01228903
Status:
COMPLETED
Last Update Posted:
2017-06-28
First Post:
2010-10-25
Is NOT Gene Therapy:
True
Has Adverse Events:
True
Brief Title:
Uric Acid and the Endothelium in CKD
Sponsor:
University of Colorado, Denver
Organization:
Study Overview
Official Title:
Is Uric Acid a Mediator of Endothelial Dysfunction in Patients With Chronic Kidney Disease?
Status:
COMPLETED
Status Verified Date:
2017-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will test the hypothesis that uric acid impairs the function of vessels in patients with kidney disease
Detailed Description:
The purpose of the study is to understand the effect of lowering serum uric acid levels on vascular function in individuals with chronic kidney disease by comparing the effects of:
1\) Allopurinol therapy and 2) Placebo.
Patients will receive: 3 month study drug (either allopurinol or placebo), with assessment of serum uric acid levels and vascular function.
1\) Allopurinol therapy and 2) Placebo.
Patients will receive: 3 month study drug (either allopurinol or placebo), with assessment of serum uric acid levels and vascular function.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| K23DK088833 | NIH | None | https://reporter.nih.gov/quic… | View |