Ignite Creation Date:
2024-05-06 @ 7:56 PM
Last Modification Date:
2024-10-26 @ 3:17 PM
Study NCT ID:
NCT06193083
Status:
RECRUITING
Last Update Posted:
2024-04-12
First Post:
2023-12-21
Brief Title:
DEprescribing Perceptions of PAtients Living With Advanced Cancer
Sponsor:
Nantes University Hospital
Organization:
Nantes University Hospital
Study Overview
Official Title:
DEprescribing Perceptions of PAtients Living With Advanced Cancer A Multicentre Prospective Mixed Observational Study
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DEPAL
Brief Summary:
Polymedication in palliative oncology care is a real public health problem This phenomenon has been shown to increase the risk of iatrogenesis reduce patients quality of life and increase healthcare costs For many years health policies have been developed in geriatrics to reduce polymedication through deprescription tools
Recently palliative care initiatives have been introduced but without having studied the potential specificities of this population younger with a different care dynamic and life trajectory It is important to better understand this populations perceptions of deprescribing in order to adapt toolsactions to make these approaches more efficient
The primary aim of this study is to investigate patients perceptions of deprescribing in palliative cancer care and the secondary aim is to investigate factors that may influence patients attitudes and beliefs about deprescribing At the same time we will study the psychometric properties of the rPATD Revised Patients Attitudes Towards Deprescribing in this population a standardized questionnaire validated in geriatric medicine to assess patients perceptions of deprescriptionAn ancillary study will be carried out to investigate the link between patients health literacy and their perception of deprescribing health literacy is defined as the ability to acquire understand and use information in ways that promote and maintain good health
To meet our objectives we will conduct a 3-year national prospective observational multicenter study with an exploratory sequential mixed design The study will comprise an initial qualitative phase Semi-directed individual interviews using a descriptive approach will be carried out around 25 patients over an 8-month period Following analysis of the qualitative data we will then carry out a quantitative study to determine the distribution of the different profiles within this population and the factors influencing the perception of deprescription The self-administered questionnaires rPATD and BMQ medication beliefs questionnaire potentially supplemented by other items following analysis of the qualitative data will be administered to 300 patients over a 12-month periodThe ancillary study will be carried out during this second phase using a validated self-questionnaire to assess patients level of literacy
Thanks to the different results we will improve our knowledge of the perception of deprescription in palliative oncology care in order to develop approaches adapted to the specificities of our population to reduce polymedication and thus improve the quality of life of our patients and reduce the risks of iatrogenia
Recently palliative care initiatives have been introduced but without having studied the potential specificities of this population younger with a different care dynamic and life trajectory It is important to better understand this populations perceptions of deprescribing in order to adapt toolsactions to make these approaches more efficient
The primary aim of this study is to investigate patients perceptions of deprescribing in palliative cancer care and the secondary aim is to investigate factors that may influence patients attitudes and beliefs about deprescribing At the same time we will study the psychometric properties of the rPATD Revised Patients Attitudes Towards Deprescribing in this population a standardized questionnaire validated in geriatric medicine to assess patients perceptions of deprescriptionAn ancillary study will be carried out to investigate the link between patients health literacy and their perception of deprescribing health literacy is defined as the ability to acquire understand and use information in ways that promote and maintain good health
To meet our objectives we will conduct a 3-year national prospective observational multicenter study with an exploratory sequential mixed design The study will comprise an initial qualitative phase Semi-directed individual interviews using a descriptive approach will be carried out around 25 patients over an 8-month period Following analysis of the qualitative data we will then carry out a quantitative study to determine the distribution of the different profiles within this population and the factors influencing the perception of deprescription The self-administered questionnaires rPATD and BMQ medication beliefs questionnaire potentially supplemented by other items following analysis of the qualitative data will be administered to 300 patients over a 12-month periodThe ancillary study will be carried out during this second phase using a validated self-questionnaire to assess patients level of literacy
Thanks to the different results we will improve our knowledge of the perception of deprescription in palliative oncology care in order to develop approaches adapted to the specificities of our population to reduce polymedication and thus improve the quality of life of our patients and reduce the risks of iatrogenia
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None