Ignite Creation Date:
2024-05-06 @ 7:55 PM
Last Modification Date:
2024-10-26 @ 3:17 PM
Study NCT ID:
NCT06187298
Status:
COMPLETED
Last Update Posted:
2024-01-29
First Post:
2023-12-16
Brief Title:
Effect of Oral Combined Berberine and Curcumin Pharmacological Therapy on IBS
Sponsor:
Liaquat University of Medical Health Sciences
Organization:
Liaquat University of Medical Health Sciences
Study Overview
Official Title:
The Adjuvant Synergistic Therapeutic Effect of Oral Berberine and Curcumin Alleviates Symptoms of Irritable Bowel Syndrome Results From a Real-life Setting Clinical Intervention Study
Status:
COMPLETED
Status Verified Date:
2024-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Irritable bowel syndrome IBS is a prevalent chronic functional gastrointestinal GI disorder characterized by recurrent abdominal discomfort pain associated with altered bowel movements IBS has a considerable negative impact on peoples quality of life QoL There is currently no specific treatment available for IBS most of the therapeutic management is symptomatic Reported evidence suggest that BBR and CUR can alleviate symptoms of IBS through their multiple pharmacological effects including preventing stress-induced intestinal inflammation and visceral hypersensitivity reducing bowel motility and regulating intestinal permeability gut microme and gut-brain axis
Detailed Description:
Aim of the study
The present clinical study aimed to assess the synergestic therapeutic effect of a combined supplement of standardised extract of BBR and CUR Enterophytol PLUS 200 mg BBR 49 mg CUR in the management of IBS
Method This was an in real-life setting pragmatic observational retrospective non-controlled and non-randomized clinical trial involving 146 patients with IBS enrolled in General Practitioner clinics and Pharmacies in Belgium from Aug 2020 to May 2022 The supplement was used as two tablets daily for 2-months alongside routine IBS care
The present clinical study aimed to assess the synergestic therapeutic effect of a combined supplement of standardised extract of BBR and CUR Enterophytol PLUS 200 mg BBR 49 mg CUR in the management of IBS
Method This was an in real-life setting pragmatic observational retrospective non-controlled and non-randomized clinical trial involving 146 patients with IBS enrolled in General Practitioner clinics and Pharmacies in Belgium from Aug 2020 to May 2022 The supplement was used as two tablets daily for 2-months alongside routine IBS care
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None