Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005519
Status:
COMPLETED
Last Update Posted:
2016-05-13
First Post:
2000-05-25
Brief Title:
Prospective Study of Diet and Cardiovascular Disease
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2004-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine associations between various dietary elements and the risk of coronary heart disease and stroke
Detailed Description:
BACKGROUND
Cardiovascular disease is the leading cause of death among residents of the United States The effect of dietary cholesterol and fat on risk of coronary heart disease CHD and stroke has been examined extensively in epidemiologic studies However the results from these studies are inconsistent Furthermore the association between some other key elements of diet and risk of CHD and stroke has been insufficiently studied in epidemiologic studies
DESIGN NARRATIVE
The study examines prospectively the association between 1 dietary intake of trans-unsaturated fat and the risk of coronary heart disease and 2 dietary intake of total saturated and unsaturated fats and risk of stroke 3 dietary intake of vegetable and animal protein and risk of stroke 4 dietary intake of total and water-soluble fiber and risk of coronary heart disease and stroke 5 dietary intake of sodium and potassium and risk of coronary heart disease and stroke 6 dietary intake of vitamin C carotenoids vitamin E and folic acid and the risk of coronary heart disease and stroke and 7 specific foods such as fish beans fruits and vegetables and the risk of coronary heart disease and stroke In addition the association of baseline serum vitamin A vitamin C and folate to the risk of coronary heart disease and stroke will be investigated
Data from the NHANES1 Epidemiologic Follow-Up Study NHEFS will be used to test the hypotheses The NHEFS is an on-going prospective cohort study being conducted in 14407 United States men and women aged 25 to 74 years by the National Center for Health Statistics NCHS The baseline data including a 24-hour dietary recall and food frequency questionnaire as well as important cardiovascular risk factors were collected during 1971-75 The follow-up data were collected during 1982 to 1984 1986 1987 and 1992 The follow-up data were obtained by means of an interview medical records from health care facilities and death certificates for all decedents In the study the investigators will re-code dietary data and calculate dietary nutrients using the ESHA Nutrient Database They will also analyze the relationship of dietary nutrients and specific foods to risk of CHD and stroke
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Cardiovascular disease is the leading cause of death among residents of the United States The effect of dietary cholesterol and fat on risk of coronary heart disease CHD and stroke has been examined extensively in epidemiologic studies However the results from these studies are inconsistent Furthermore the association between some other key elements of diet and risk of CHD and stroke has been insufficiently studied in epidemiologic studies
DESIGN NARRATIVE
The study examines prospectively the association between 1 dietary intake of trans-unsaturated fat and the risk of coronary heart disease and 2 dietary intake of total saturated and unsaturated fats and risk of stroke 3 dietary intake of vegetable and animal protein and risk of stroke 4 dietary intake of total and water-soluble fiber and risk of coronary heart disease and stroke 5 dietary intake of sodium and potassium and risk of coronary heart disease and stroke 6 dietary intake of vitamin C carotenoids vitamin E and folic acid and the risk of coronary heart disease and stroke and 7 specific foods such as fish beans fruits and vegetables and the risk of coronary heart disease and stroke In addition the association of baseline serum vitamin A vitamin C and folate to the risk of coronary heart disease and stroke will be investigated
Data from the NHANES1 Epidemiologic Follow-Up Study NHEFS will be used to test the hypotheses The NHEFS is an on-going prospective cohort study being conducted in 14407 United States men and women aged 25 to 74 years by the National Center for Health Statistics NCHS The baseline data including a 24-hour dietary recall and food frequency questionnaire as well as important cardiovascular risk factors were collected during 1971-75 The follow-up data were collected during 1982 to 1984 1986 1987 and 1992 The follow-up data were obtained by means of an interview medical records from health care facilities and death certificates for all decedents In the study the investigators will re-code dietary data and calculate dietary nutrients using the ESHA Nutrient Database They will also analyze the relationship of dietary nutrients and specific foods to risk of CHD and stroke
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R03HL061954 | NIH | None | httpsreporternihgovquickSearchR03HL061954 |