Ignite Creation Date:
2024-05-06 @ 7:55 PM
Last Modification Date:
2024-10-26 @ 3:17 PM
Study NCT ID:
NCT06188013
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-01-03
First Post:
2023-12-11
Brief Title:
Proteomic Study of Plasma Exosomes in Patients With Diabetic Retinopathy
Sponsor:
Xuanwu Hospital Beijing
Organization:
Xuanwu Hospital Beijing
Study Overview
Official Title:
Proteomic Study of Plasma Exosomes in Patients With Diabetic Retinopathy
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Objective Explore the biomarkers related to proliferative diabetic retinopathy by analyzing the protein expression profile changes of plasma exosomes in patients with difference phases of diabetic retinopathy and investigate potential molecular mechanisms and therapeutic targets Methods Enrich exosomes from plasma by column extraction method NTA WB and TEM were used to characterize the obtained exosomes and exosome proteinomics was performed by chromatographymass spectrometry Corhorts The study was divided into four groups a healthy control group a diabetic without diabetic retinopathy group a non-proliferative diabetic retinopathy group and a proliferative diabetic retinopathy group with 6 cases in each group
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None