Ignite Creation Date:
2024-05-06 @ 7:52 PM
Last Modification Date:
2024-10-26 @ 3:15 PM
Study NCT ID:
NCT06165224
Status:
RECRUITING
Last Update Posted:
2024-03-15
First Post:
2023-12-03
Brief Title:
A Bidirectional Cohort Study of COMMD10 Expression in Tumor Tissues for Predicting Radiosensitivity
Sponsor:
Nanfang Hospital Southern Medical University
Organization:
Nanfang Hospital Southern Medical University
Study Overview
Official Title:
A Bidirectional Cohort Study of COMMD10 Expression in Tumor Tissues for Predicting Radiosensitivity
Status:
RECRUITING
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Radiotherapy is one of the main treatments for malignant tumors and according to authoritative estimates about 70 of patients with malignant tumors should receive radiotherapy However radiation resistance limits its application and clinical curative effect To find suitable radiation resistance markers and identify patients with radiation resistance early part of the patients with appropriate radiotherapy sensitization agent or choose other more efficient and low toxicity of treatment for improving the prognosis of patients improve the quality of survival is of great significance it is also the difficult point in the present study However there are no effective biomarkers to predict radiosensitivity Through our previous basic research and analysis of clinical tumor tissues we have found that the low expression of copper metabolism domain protein 10 COMMD10 is associated with radioresistance and COMMD10 is an effective marker for predicting radiosensitivity We planned to conduct a single-center prospective cohort study to verify the reliability of COMMD10 as a predictive marker for radiosensitivity in pan-cancer patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None