Ignite Creation Date:
2024-05-06 @ 7:52 PM
Last Modification Date:
2024-10-26 @ 3:15 PM
Study NCT ID:
NCT06168136
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-12-13
First Post:
2023-12-01
Brief Title:
Effects of Medical High Protein Nutrition on the Muscle Mass in Adult ICU Patients
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Effects of Medical High Protein Nutrition on the Muscle Mass in Adult ICU Patients
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The use of ultrasound in clinical practice is feasible for monitoring muscle mass in critically ill patients Assessment of muscle mass by ultrasound is clinically relevant and adds value for guiding therapeutic interventions such as nutritional and physical therapy interventions to maintain muscle mass and promote recovery in critically ill patients
Detailed Description:
Critical illness is characterized by substantial hormone- and cytokine-mediated protein metabolism changes in various organs leading to increased breakdown and decreased synthesis rates Consequently a considerable and life-threatening loss of muscle mass occurs Medical therapeutic measures such as long-term sedation and mechanical ventilation during ICU stay can further enhance this muscle degradation up to 2 muscle mass per day leading to clinically relevant symptoms known as ICU-acquired weakness Nutritional modulation particularly of dietary amino acids may have benefits to prevent or attenuate disease-induced muscle wasting while there are several accurate muscle mass measurement methods and techniques including computed tomography CT scan bio-impedance analysis and ultrasound not all are routinely feasible in clinical ICU practice The use of ultrasound in assessing muscle mass in critically ill patients has gained much attention recently as it is non-invasive and can easily be utilized at the bedside There are two main goals for the assessment of muscle mass first to assess the current muscle mass for the patient as part of nutritional diagnosis and thereby risk stratification and second to monitor the progression of muscle loss andor recovery of muscle mass and create opportunity to examine the effectiveness of therapeutic interventions to reduce muscle loss andor promote muscle recovery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None