Ignite Creation Date:
2024-05-06 @ 7:52 PM
Last Modification Date:
2024-10-26 @ 3:15 PM
Study NCT ID:
NCT06164483
Status:
RECRUITING
Last Update Posted:
2024-05-08
First Post:
2023-12-01
Brief Title:
Auditory Functions in Patients With Multiple Sclerosis
Sponsor:
University of Catania
Organization:
University of Catania
Study Overview
Official Title:
Electrophysiological Studies of Auditory Functions and CSF Analyses in Patients With Multiple Sclerosis
Status:
RECRUITING
Status Verified Date:
2024-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study will analyze the auditory functions of patients with Multiple Sclerosis using auditory tests like pure tone auditory test speech perception test Auditory Brain Response ABR and Distortion Product Otoacustic Emission DPOAE CSF will be collected by lumbar puncture and analyzed looking for inflammatory markers
The results of DPOAE and CSF will be correlated to identify statistically significant correlation
The results of DPOAE and CSF will be correlated to identify statistically significant correlation
Detailed Description:
Case-Control study
Tools for patients selection and inclusion in the study
STEP one
Full medical records detailed for neurological diseases
Brain and spinal cord MRI performed 12 months n1 before and most recent one n2
Lumbar puncture
Blood test
Questionnaire for screening hearing disorders
App for screening hearing loss
STEP two
Pure Tone Auditory test Tympanometry and Stapedial Reflex
Speech Perception test
In case of tinnitus tinnitus questionnaire and acuphenometry
DPOAEs
ABR
STEP three in case of Hearing impairment
- MRI Tractography
Tools for patients selection and inclusion in the study
STEP one
Full medical records detailed for neurological diseases
Brain and spinal cord MRI performed 12 months n1 before and most recent one n2
Lumbar puncture
Blood test
Questionnaire for screening hearing disorders
App for screening hearing loss
STEP two
Pure Tone Auditory test Tympanometry and Stapedial Reflex
Speech Perception test
In case of tinnitus tinnitus questionnaire and acuphenometry
DPOAEs
ABR
STEP three in case of Hearing impairment
- MRI Tractography
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None