Ignite Creation Date:
2024-05-06 @ 7:51 PM
Last Modification Date:
2024-10-26 @ 3:15 PM
Study NCT ID:
NCT06162234
Status:
RECRUITING
Last Update Posted:
2023-12-27
First Post:
2023-12-01
Brief Title:
Wuhan High Myopia Study
Sponsor:
Renmin Hospital of Wuhan University
Organization:
Renmin Hospital of Wuhan University
Study Overview
Official Title:
Long Term Observation of Ocular Structure and Visual Function in Eyes With High MyopiaWuhan High Myopia Study
Status:
RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LOVE-WH
Brief Summary:
The study aims to observe the long-term changes of ocularespecially fundus structure and visual function in patients with high myopia so as to provide evidence for the prevention diagnosis and prognosis of high myopia
Detailed Description:
High myopia is defined as a refractive error of -600D or an axial length greater than 26mm In recent years the population of highly myopic individuals has been increasing rapidly Scholars predict that if no effective interventions are taken the global incidence rate of myopia is expected to increase from 229 in 2000 to 498 in 2050 and the visual impairment caused by high myopia will be seven times higher than in 2000 on a global scale In China a survey conducted by the National Health Commission in 2018 found that highly myopic students accounted for 219 of third-year high school students indicating that high myopia has become a major public health issue due to its prevalence among younger populations
In recent years with the development of ocular imaging technologies such as optical coherence tomography OCT and corresponding image analysis techniques high-resolution non-invasive fast and in vivo retinal imaging has become more accessible This has led to the discovery and exploration of various imaging parameters related to optic disc and macula changes in highly myopic patients We will conduct a 4 years prospective cohort study in the population of 1000 high myopia and controls which have established in mainly college student population using the latest OCT-A and SS-OCT to observe the long-term changes of fundus structure combined with visual function in patients with high myopia and explore biomarkers affecting visual function so as to provide basis for prevention and control of high myopia and prognosis
In recent years with the development of ocular imaging technologies such as optical coherence tomography OCT and corresponding image analysis techniques high-resolution non-invasive fast and in vivo retinal imaging has become more accessible This has led to the discovery and exploration of various imaging parameters related to optic disc and macula changes in highly myopic patients We will conduct a 4 years prospective cohort study in the population of 1000 high myopia and controls which have established in mainly college student population using the latest OCT-A and SS-OCT to observe the long-term changes of fundus structure combined with visual function in patients with high myopia and explore biomarkers affecting visual function so as to provide basis for prevention and control of high myopia and prognosis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None