Ignite Creation Date:
2024-05-06 @ 7:51 PM
Last Modification Date:
2024-10-26 @ 3:15 PM
Study NCT ID:
NCT06155656
Status:
COMPLETED
Last Update Posted:
2024-04-22
First Post:
2023-11-07
Brief Title:
Effects of Pea Proteins with Different Degrees of Processing on Postprandial Metabolism in Healthy Adults
Sponsor:
University of Bonn
Organization:
University of Bonn
Study Overview
Official Title:
Acute Effects of Pea Proteins with Different Degrees of Processing on Postprandial Metabolism in Healthy Women and Men
Status:
COMPLETED
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to investigate the postprandial metabolic responses to plant-based protein ingredients of different degrees of processing pea protein concentrate isolate and extrudate and in comparison to whey protein in healthy adults Therefore young healthy subjects consume 4 test meals with 25 g of protein from pea protein concentrate pea protein isolate pea protein extrudate or whey protein in a randomized order In a postprandial period of 6 hours parameters of protein and glucose metabolism ia plasma amino acids gastric emptying and hungersatiety are analysed It is assumed that the plasma amino acid profile after plant protein ingestion differs depending on processing level of the protein ingredients and in comparison to whey protein
Detailed Description:
In a randomized crossover-design 20 healthy women and men consume 4 test meals containing either 25 g of protein from plant protein ingredients pea protein concentrate isolate or extrudate or whey protein together with 1 g paracetamol which is used as a marker for gastric emptying
During a postprandial period of 6 hours parameters of protein metabolism eg amino acids in plasma and urine glucose metabolism plasma glucose serum insulin and gastric emptying rate based on plasma paracetamol are analysed Furthermore subjective hungersatiety and acceptance of the meals are assed using visual analogue scales Each intervention arm will be separated by a washout period of at least 7 days
During a postprandial period of 6 hours parameters of protein metabolism eg amino acids in plasma and urine glucose metabolism plasma glucose serum insulin and gastric emptying rate based on plasma paracetamol are analysed Furthermore subjective hungersatiety and acceptance of the meals are assed using visual analogue scales Each intervention arm will be separated by a washout period of at least 7 days
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None