Ignite Creation Date:
2024-05-06 @ 7:51 PM
Last Modification Date:
2024-10-26 @ 3:15 PM
Study NCT ID:
NCT06155227
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-12-26
First Post:
2023-11-23
Brief Title:
Blood Flow Restriction With Aerobic Exercise in Frail Older Adults
Sponsor:
National Cheng Kung University
Organization:
National Cheng Kung University
Study Overview
Official Title:
Effect of Aerobic Exercise Combined With Blood Flow Restriction on Cardiopulmonary Function and Functional Activities in Frail Older Adults
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
BackgroundFrailty is most often defined as a syndrome of physiological decline in late life characterized by marked vulnerability to adverse health outcomes Exercise intervention including aerobic exercise training has been proven to be effective in improving aerobic capacity and frail condition in elderly Recently a novel training method using blood flow restriction BFR combined with aerobic exercise has shown positive effects on muscles strength and physical function in healthy elderly This training method only required lower exercise intensity compared with traditional aerobic exercise to observe improvement However it is still unclear whether aerobic exercise training combined with BFR could also improve aerobic capacity and physical function in frail older adults Therefore the aim of this study will be to investigate the effect of aerobic exercise combined with BFR on cardiopulmonary function and functional activities in frail older adults
Method This study will be an assessor-blind randomized controlled trialParticipants aged over 65 years old with more than one item positive of Fried frailty phenotype assessment results will be recruited from the hospital and nearby communities The participants will be randomly assigned to one of two training groups aerobic exercise with BFR and only aerobic exercise The exercise will be executed 30 minutessession three sessionsweek for six weeks Cardiopulmonary function and performance of functional activities will be assessed at pre-training 3 weeks after training post-training and 3- and 6-week follow-up
Method This study will be an assessor-blind randomized controlled trialParticipants aged over 65 years old with more than one item positive of Fried frailty phenotype assessment results will be recruited from the hospital and nearby communities The participants will be randomly assigned to one of two training groups aerobic exercise with BFR and only aerobic exercise The exercise will be executed 30 minutessession three sessionsweek for six weeks Cardiopulmonary function and performance of functional activities will be assessed at pre-training 3 weeks after training post-training and 3- and 6-week follow-up
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None