Ignite Creation Date:
2024-05-05 @ 9:53 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001489
Status:
COMPLETED
Last Update Posted:
2008-03-04
First Post:
1999-11-03
Brief Title:
Effect of Vigabatrin on Brain Blood Flow and Glucose Metabolism
Sponsor:
National Institute of Neurological Disorders and Stroke NINDS
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
The Effect of Vigabatrin on Cerebral Blood Flow and Glucose Metabolism
Status:
COMPLETED
Status Verified Date:
1999-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study is designed to test the effects of vigabatrin gamma-vinyl-GABA an experimental drug used for the treatment of epilepsy The study will use positron emission tomography PET scan to detect areas of the brain receiving increased blood flow and using increased amounts of glucose Increases in blood flow and glucose use are good indicators of brain activity
Researchers are interested in determining the effects of Vigabatrin on brain blood flow and glucose use
Researchers are interested in determining the effects of Vigabatrin on brain blood flow and glucose use
Detailed Description:
This double-blind placebo-controlled parallel design protocol will investigate the effects of gamma-vinyl-GABA vigabatrin--GVG an experimental antiepileptic drug on cerebral glucose metabolism LCMRglc blood flow CBF and seizure frequency in patients with uncontrolled complex partial CPS and secondary generalized seizures GTCS Positron Emission Tomography PET will be used to measure CBF and LCMRglc
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 95-N-0008 | None | None | None |