Viewing Study NCT06153264



Ignite Creation Date: 2024-05-06 @ 7:50 PM
Last Modification Date: 2024-10-26 @ 3:15 PM
Study NCT ID: NCT06153264
Status: COMPLETED
Last Update Posted: 2024-01-02
First Post: 2023-11-22

Brief Title: Neural Mobilization on Multiple Sclerosis
Sponsor: Kahramanmaras Sutcu Imam University
Organization: Kahramanmaras Sutcu Imam University

Study Overview

Official Title: Effect of Neurodynamic Mobilization Exercises on Pain Muscle Strength and Manual Dexterity in Multiple Sclerosis Patients
Status: COMPLETED
Status Verified Date: 2024-08
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Current treatments for pain in MS patients include the use of non-pharmacological interventions such as electrotherapy and exercise as well as pharmacological treatments Neurodynamic mobilization exercises are an intervention that aims to restore homeostasis in and around the nervous system by activating the nervous system itself or the structures surrounding the nervous system Neurodynamic mobilization facilitates movement between neural structures and their environment through manual techniques and exercise Human and animal studies reveal that neurodynamic mobilization reduces intraneural edema improves intraneural fluid distribution reduces thermal and mechanical hyperalgesia and reverses increased immune responses following a nerve injury
Detailed Description: Multiple Sclerosis MS is a chronic neurological disease characterized by local inflammation gliosis and demyelination in the central nervous system CNS It is characterized by demyelinating plaques seen in the brain and medulla spinalis Many different symptoms can be seen depending on the affected areas in the CNS One of the common symptoms in these patients is pain Approximately 50 of patients complain of pain at some point in their lives and in 20 of them pain is one of the initial symptoms Pain may originate from the musculoskeletal system It may also develop due to inflammation and upper motor neuron damage and may have a neuropathic character As a result pain in MS negatively affects patients physical emotional functions and quality of life

Current treatments for pain in MS patients include the use of non-pharmacological interventions such as electrotherapy and exercise as well as pharmacological treatments Neurodynamic mobilization exercises are an intervention that aims to restore homeostasis in and around the nervous system by activating the nervous system itself or the structures surrounding the nervous system Neurodynamic mobilization facilitates movement between neural structures and their environment through manual techniques and exercise Human and animal studies reveal that neurodynamic mobilization reduces intraneural edema improves intraneural fluid distribution reduces thermal and mechanical hyperalgesia and reverses increased immune responses following a nerve injury

As a result of this study it is thought that the determination of effective treatment methods for pain which is a common symptom of MS patients will increase the patients muscle strength and dexterity

The aim of the study is to examine the effects of neurodynamic mobilization exercises on pain muscle strength and dexterity in Multiple Sclerosis patients

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: False
Is a FDA Regulated Device?: False
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None