Ignite Creation Date:
2024-05-06 @ 7:50 PM
Last Modification Date:
2024-10-26 @ 3:14 PM
Study NCT ID:
NCT06150105
Status:
COMPLETED
Last Update Posted:
2023-12-06
First Post:
2023-11-13
Brief Title:
Changes in the Hormonal and Inflammatory Profile of Young Sprint- and Endurance-trained Athletes
Sponsor:
Poznan University of Physical Education
Organization:
Poznan University of Physical Education
Study Overview
Official Title:
Changes in the Hormonal and Inflammatory Profile of Young Sprint- and Endurance-trained Athletes Following a Sports Camp
Status:
COMPLETED
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CHIPYA
Brief Summary:
One essential element of athlete training is conditioning camps where athletes undergo a rigorous and targeted training schedule to prepare for upcoming sporting events During sports camps due to the accumulation of a large number of training units including high-intensity exercises athletes react with post-exercise overload acute fatigue and overreaching which can become a chronic overtraining syndrome Overtraining syndrome is a very specific and severe condition where overtraining without adequate rest and recovery leads to performance decrements lasting more than 2-3 months coupled with a mood disturbance The exact etiology and pathogenesis are unknown and actively being investigated
During training camps the balance between training volumes and recovery is often a delicate one and the accumulation of exercise-induced stress may exceed the capacity of both neuroendocrine and immune adaptation leading to an alteration of physiological functions decreasing adaptation to performance impairment of psychological processing immunological dysfunction and biochemical abnormalities Moreover there is currently a lack of biomarkers accessible to assist in diagnosing and whats even more important - help to prevent the overtraining syndrome except for the continued presence of unexplained underperformance despite athletes adequate rest and recovery
Thus this study aims to explain how long and intensive training for endurance affects the hormonal and immune systems of young athletes
The main questions it aims to answer are
1 How does intense training influence hormonal and immune responses in young trained athletes
2 Does training specialization affect the hormonal and immune response to intense training
During training camps the balance between training volumes and recovery is often a delicate one and the accumulation of exercise-induced stress may exceed the capacity of both neuroendocrine and immune adaptation leading to an alteration of physiological functions decreasing adaptation to performance impairment of psychological processing immunological dysfunction and biochemical abnormalities Moreover there is currently a lack of biomarkers accessible to assist in diagnosing and whats even more important - help to prevent the overtraining syndrome except for the continued presence of unexplained underperformance despite athletes adequate rest and recovery
Thus this study aims to explain how long and intensive training for endurance affects the hormonal and immune systems of young athletes
The main questions it aims to answer are
1 How does intense training influence hormonal and immune responses in young trained athletes
2 Does training specialization affect the hormonal and immune response to intense training
Detailed Description:
Twenty-four young male and female athletes specializing in athletics disciplines such as sprint hurdles 100m 110m and endurance race walk 5000m and 10000m volunteered to take part in this study Investigation was held during 9 days of the training camp preparatory period general preparation sub-period which was aimed at increasing the endurance and flexibility of athletes During the training camp all subjects occupied the same accommodations and followed the same training plan and diet schedules The camp regime included 2 training sessions per day lasting 4 hours per day and a total of 21 hours per 9 days Blood samples were taken always in the same conditions from the antecubital veins Participants were seated in a recumbent position for a minimum of 10 minutes before blood draws to stabilize the hydrostatic condition Before collection of the first sample rested baseline participants were asked to avoid any intense exercise at least 24 hours before sampling Next samples were taken after 4 days and after another 5 days of training camp in total after 9 days The concentration of catecholamines epinephrine and norepinephrine in serum was measured as well and the responsiveness of the adrenal medulla to the sympathetic nervous activity was estimated by the ratio ENE calculated Also concentrations of cortisol hs-CRP and myoglobin were measured and changes in blood morphology were estimated
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None