Ignite Creation Date:
2024-05-06 @ 7:50 PM
Last Modification Date:
2024-10-26 @ 3:15 PM
Study NCT ID:
NCT06153914
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-12-01
First Post:
2023-11-22
Brief Title:
SALT for Patients With Hepatic Cirrhosis
Sponsor:
RenJi Hospital
Organization:
RenJi Hospital
Study Overview
Official Title:
A Clinical Study of the Effectiveness of Sequential Adult Left Lateral Lobe Liver Transplantation in Patients With Hepatitis B Cirrhosis a Single-center Prospective Single-arm Study
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hepatitis B virus HBV infection is a very difficult public health problem in the world Patients often experience the trilogy of hepatitis-cirrhosis-liver cancer Patients with decompensated cirrhosis may develop a variety of complications such as portal hypertension hypersplenism esophageal and gastric variceal bleeding ascites spontaneous peritonitis hepatic encephalopathy etc
Liver transplantation is the only way to cure hepatitis B cirrhosis However the shortage of liver donors still severely limits its development In 2015 Line and others proposed a new surgical method namely resection and partial liver segment 2-3 transplantation with delayed total hepatectomy RAPID This surgery innovatively combines auxiliary liver transplantation and ALLPS surgery which can greatly alleviate the problem of liver donor shortage and improve the overall prognosis of the above-mentioned patients
Our center has designed the Sequential Adult Left Lateral Liver Transplantation SALT procedure based on the principles of RAPID surgery and the characteristics of patients with cirrhosis Compared with RAPID surgery SALT surgery can dynamically monitor and regulate the blood flow of the residual liver and transplanted liver reducing the risk caused by portal hypertension This study will evaluate the safety and effectiveness of SALT in the treatment of post-hepatitis B cirrhosis
Liver transplantation is the only way to cure hepatitis B cirrhosis However the shortage of liver donors still severely limits its development In 2015 Line and others proposed a new surgical method namely resection and partial liver segment 2-3 transplantation with delayed total hepatectomy RAPID This surgery innovatively combines auxiliary liver transplantation and ALLPS surgery which can greatly alleviate the problem of liver donor shortage and improve the overall prognosis of the above-mentioned patients
Our center has designed the Sequential Adult Left Lateral Liver Transplantation SALT procedure based on the principles of RAPID surgery and the characteristics of patients with cirrhosis Compared with RAPID surgery SALT surgery can dynamically monitor and regulate the blood flow of the residual liver and transplanted liver reducing the risk caused by portal hypertension This study will evaluate the safety and effectiveness of SALT in the treatment of post-hepatitis B cirrhosis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None