Ignite Creation Date:
2024-05-06 @ 7:49 PM
Last Modification Date:
2024-10-26 @ 3:14 PM
Study NCT ID:
NCT06141239
Status:
NOT_YET_RECRUITING
Last Update Posted:
2024-02-08
First Post:
2023-11-15
Brief Title:
2D3D Imaging to Analyze the Regeneration Rate of Autologous Bone
Sponsor:
Chang Gung Memorial Hospital
Organization:
Chang Gung Memorial Hospital
Study Overview
Official Title:
Using 2D3D Imaging to Analyze the Regeneration Rate of Autologous Bone During Alveolar Bone Preservation Surgery Using Periodontal Valves to Completely Cover Autologous Tooth Roots Bone Substitutes and Vitamin D3 Treatment
Status:
NOT_YET_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Place a collagen plug collagen plug in the lower 23 to 12 of your tooth extraction site while giving you Vit The extracted teeth are made into autogenous tooth root thin slices and covered in your tooth extraction cavity and the skin flap raised by your flap surgery is used to cover the autologous tooth root cover to help the autologous tooth roots stabilize and heal the wound which is different from traditional surgery The difference in treatment lies in the local use of autogenous tooth root thin slices and VitD3 Collagen plug and VitD3 are already qualified medical materials and drugs on the market However there is no precedent for making thin autologous tooth root slices will be a trial of a new medical technology that has not yet been used
Detailed Description:
After tooth extraction the shape of the alveolar bone will be changed The ridge preservation method combined with the extraction socket sealing method has a significant clinical effect in preserving the vertical and horizontal directions of the alveolar bone ridge and improves the predictability of the position of the dental bridge and beautiful Since there will be different bone formation rates in different locations of the extraction cavity the literature shows that the bone formation rate is higher in the apical position of the extraction cavity while the bone formation rate is lower in the coronal location Therefore the bone formation rate is 231 under the extraction cavity Insert the collagen plug at the 2 position and carry VitD3 and place appropriate bone material at the 13 position If there is no bone material support there will be a 5060 chance that the autogenous root cover will fall off but if all bone materials are placed at Under 3D imaging technology it is impossible to clearly distinguish whether the image is the bone material itself or the formation of autogenous bone Collagen plug uses its biocompatibility and absorbability and other biological properties to quickly stop bleeding and stabilize the clot in the wound and has an impact on fibroblasts It also has a chemotactic effect accelerating the healing of extraction sockets and can also promote the secretion of immature osteoid from the extracellular matrix VitD3 can induce the differentiation of mesenchymal cells into osteoblasts and promote bone formation Try to use these two Can the combination of biological materials and pharmaceuticals increase the bone formation rate In addition a cover made of autologous tooth root slices can be used for tooth extraction cavity sealing to prevent the bone material from being disturbed and damaged by the external environment However the autologous tooth root cover has a chance of falling off so The skin flap opened by flap surgery is used to cover the autogenous tooth root cap which strengthens the fixation and helps primary wound closure reduces saliva contamination of bone graft materials and accelerates wound healing At the same time it does not increase material costs or the patients financial burden Observe and track the treatment effect and explore whether the shedding rate of autogenous root caps with and without valve coverage has an impact on alveolar ridge resorption In addition medical imaging technology is used to replace expensive and complicated biopsies reduce the damage caused by biopsy to the structural integrity of the extraction socket test whether there is new bone formation in the extraction socket and integrate computer tomography and intraoral scan files while observing the softness of the extraction socket Hard tissue healing status
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None