Ignite Creation Date:
2024-05-06 @ 7:48 PM
Last Modification Date:
2024-10-26 @ 3:14 PM
Study NCT ID:
NCT06144463
Status:
COMPLETED
Last Update Posted:
2023-11-28
First Post:
2023-11-13
Brief Title:
Lung Ultrasound-guided Fluid Resuscitation in Neonatal Septic Shock
Sponsor:
Guangdong Second Provincial General Hospital
Organization:
Guangdong Second Provincial General Hospital
Study Overview
Official Title:
Study on the Application Value of Fluid Resuscitation Guided by Lung Ultrasound in Neonatal Septic Shock
Status:
COMPLETED
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LUGFRINSS
Brief Summary:
object name Lung ultrasound-guided fluid resuscitation in neonatal septic shock
type of study prospective observational study goal of study The effects of severe ultrasound-assisted fluid resuscitation and conventional fluid resuscitation on the prognosis of children with neonatal septic shock were compared to evaluate the application value of the two techniques in fluid resuscitation of neonatal septic shock
research design In this study children with neonatal septic shock diagnosed in the neonatal intensive care unit of the Second People s Hospital of Guangdong Province from January 12022 to December 312023 were included in the population According to the different monitoring methods used in conventional clinical shock treatment 30 cases of fluid resuscitation assisted by severe ultrasound 30 cases of fluid resuscitation assisted by NICOM and 30 cases of conventional fluid resuscitation were collected a total of 90 cases
1 The demographic data blood examination and microbiological examination data of the two groups at admission were collected
2 The fluid volume blood lactic acid blood pressure vasoactive drugs such as dopamine and epinephrine norepinephrine mechanical ventilation renal replacement therapy and antibiotic use were collected before fluid resuscitation
3 The cumulative fluid infusion volume during fluid resuscitation 6 hours and the use of vasoactive drugs and mechanical ventilation for 6 hours were collected
4 NICU hospitalization time cumulative hospitalization time and mortality were collected
Data collection
1 The demographic data blood examination and microbiological examination data of the three groups at admission were collected
2 The fluid volume blood lactic acid blood pressure vasoactive drugs such as dopamine and adrenaline norepinephrine mechanical ventilation renal replacement therapy and antibiotic use before fluid resuscitation were collected
3 The cumulative fluid infusion volume during fluid resuscitation 6 hours and the use of vasoactive drugs and mechanical ventilation for 6 hours were collected
4 NICU hospitalization time cumulative hospitalization time and mortality were collected
type of study prospective observational study goal of study The effects of severe ultrasound-assisted fluid resuscitation and conventional fluid resuscitation on the prognosis of children with neonatal septic shock were compared to evaluate the application value of the two techniques in fluid resuscitation of neonatal septic shock
research design In this study children with neonatal septic shock diagnosed in the neonatal intensive care unit of the Second People s Hospital of Guangdong Province from January 12022 to December 312023 were included in the population According to the different monitoring methods used in conventional clinical shock treatment 30 cases of fluid resuscitation assisted by severe ultrasound 30 cases of fluid resuscitation assisted by NICOM and 30 cases of conventional fluid resuscitation were collected a total of 90 cases
1 The demographic data blood examination and microbiological examination data of the two groups at admission were collected
2 The fluid volume blood lactic acid blood pressure vasoactive drugs such as dopamine and epinephrine norepinephrine mechanical ventilation renal replacement therapy and antibiotic use were collected before fluid resuscitation
3 The cumulative fluid infusion volume during fluid resuscitation 6 hours and the use of vasoactive drugs and mechanical ventilation for 6 hours were collected
4 NICU hospitalization time cumulative hospitalization time and mortality were collected
Data collection
1 The demographic data blood examination and microbiological examination data of the three groups at admission were collected
2 The fluid volume blood lactic acid blood pressure vasoactive drugs such as dopamine and adrenaline norepinephrine mechanical ventilation renal replacement therapy and antibiotic use before fluid resuscitation were collected
3 The cumulative fluid infusion volume during fluid resuscitation 6 hours and the use of vasoactive drugs and mechanical ventilation for 6 hours were collected
4 NICU hospitalization time cumulative hospitalization time and mortality were collected
Detailed Description:
Efficacy evaluation The main efficacy criteria NICU hospitalization time and cumulative hospitalization time mortality Secondary efficacy criteria cumulative fluid volume during fluid resuscitation 6 hours and use of vasoactive drugs and mechanical ventilation for 6 hours
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None