Ignite Creation Date:
2024-05-06 @ 7:46 PM
Last Modification Date:
2024-10-26 @ 3:13 PM
Study NCT ID:
NCT06133725
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-11-15
First Post:
2023-10-23
Brief Title:
TAPB Combined With RSB Versus ESPB for Postoperative Analgesia After Laparoscopic Liver Resection
Sponsor:
Zhangyi
Organization:
Tongji Hospital
Study Overview
Official Title:
Transversus Abdominis Plane Block Combined With Rectus Sheath Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Laparoscopic Liver Resection
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Postoperative pain after laparoscopic hepatectomy is composed of multiple factors and the peak pain of postoperative pain mainly occurs within the first 24 hours so it is particularly important to find an appropriate analgesic method Transversus abdominis plane block TAPB and Rectus sheath blocks RSB are widely used in abdominal surgery but too deep a needle tip during RSB may puncture abdominal organs TAPB and RSB can only provide somatic analgesia but lack visceral analgesia Recently Erector spinae plane block ESPB has been used in some studies for analgesia after abdominal surgery The purpose of this study is to compare the analgesic effect and postoperative recovery effect of erector spinae plane block and transverse abdominis plane block combined with rectus sheath block in patients undergoing laparoscopic hepatectomy Therefore this study has important clinical implications
Detailed Description:
In a double-blind randomized controlled study researchers randomized 60 patients undergoing laparoscopic hepatectomy to TAPB combined with RSB or ESPB with both groups receiving additional standardized treatment including multimodal analgesia The main outcome was the consumption of morphine within 24 hours after surgery Secondary outcomes included the number of rescue analgesia at 1h 2h 4h 8h and 24 hours after surgery VAS scores in resting and coughing at 1h 2h 4h 8h and 24h after surgery CVP values at 5 10 15 and 30min after nerve block QoR-15 patient questionnaire scores before and 24h after surgery and postoperative liver function the percentage increase of AST and ALT compare with preoperative postoperative complications and discharge time
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None