Ignite Creation Date:
2024-05-06 @ 7:46 PM
Last Modification Date:
2024-10-26 @ 3:13 PM
Study NCT ID:
NCT06126991
Status:
RECRUITING
Last Update Posted:
2024-02-01
First Post:
2023-10-30
Brief Title:
Organ Protective Effect of Cetirizine In Patients With Severe Burns
Sponsor:
Ruijin Hospital
Organization:
Ruijin Hospital
Study Overview
Official Title:
Organ Protective Effect of Histamine H1 Receptor Antagonist In Patients With Severe Burns A Clinical Study
Status:
RECRUITING
Status Verified Date:
2023-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This prospective clinical trial aims to investigate the organ protective effects of cetirizine in patients with severe burns
Detailed Description:
This is a prospective randomized single-blind parallel-controlled clinical trial The global objective is to compare the organ protective effects of the sedation and analgesia regimen midazolam fentanyl with the modified sedation and analgesia regimen midazolam fentanyl cetirizine in patients with severe burns 30 TBSA Participants will receive the intervention from admission to 72 hours post-burn Researchers will take the APACHE II scores on days 7 after admission as the main outcomes Researchers will also take other supplementary examination results into account including liver enzyme myocardial enzyme renal function haemodynamic index coagulation function and pulmonary interstitial edema
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None