Ignite Creation Date:
2024-05-06 @ 7:43 PM
Last Modification Date:
2024-10-26 @ 3:13 PM
Study NCT ID:
NCT06118242
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-11-07
First Post:
2023-10-30
Brief Title:
The Effect of Solutions Used in Oral Care on Preventing Ventilator-Associated Pneumonia
Sponsor:
Aydin Adnan Menderes University
Organization:
Aydin Adnan Menderes University
Study Overview
Official Title:
The Effect of Chlorhexidine Gluconate Sodium Bicarbonate Ozonated Water and Hypochlorous Acid Solutions Used in Oral Care on Preventing Ventilator-Associated Pneumonia
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical trial is to learn about effects of chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions used in oral care of patients on mechanical ventilation support on preventing ventilator associated pneumonia
The main questions it aims to answer are
Is there any difference between 1 chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions versus 012 chlorhexidine gluconate solution used in oral care in preventing the development of VAP Is there any difference between 1 chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions versus 012 chlorhexidine gluconate solution used in oral care in preventing the development of VAP
Researchers will compare 1 chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions to see if VAP
The main questions it aims to answer are
Is there any difference between 1 chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions versus 012 chlorhexidine gluconate solution used in oral care in preventing the development of VAP Is there any difference between 1 chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions versus 012 chlorhexidine gluconate solution used in oral care in preventing the development of VAP
Researchers will compare 1 chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions to see if VAP
Detailed Description:
Many problems may develop in patients on mechanical ventilation support in intensive care units The most important of these is ventilator-associated pneumonia VAP caused by inadequate oral care in patients on mechanical ventilator support The aim of the thesis is to examine the effect of chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions used in oral care in preventing ventilator-associated pneumonia in patients on mechanical ventilation support
This research was planned as a randomized controlled experimental study The sample of the study will consist of 105 intubated adult patients hospitalized in the Anesthesia and Reanimation Intensive Care Unit of the Republic of Turkey Ministry of Health Aydın Provincial Health Directorate Nazilli State Hospital Patients will be divided into a total of 5 groups 4 experimental and 1 control group The groups to which 1 chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions are applied will constitute the experimental group and the patients who receive oral care with 012 chlorhexidine gluconate which is routinely applied in the clinic will constitute the control group Patients will be given oral care by the nurse with determined solutions chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid 4 times a day according to the oral care protocol and the oral mucosa of all patient groups will be evaluated every morning for 7 days A deep tracheal aspirate sample will be taken and a chest x-ray will be taken on the first and seventh days after hospitalization of intubated patients The development of VAP in patients will be evaluated with the clinical pulmonary infection score
This research was planned as a randomized controlled experimental study The sample of the study will consist of 105 intubated adult patients hospitalized in the Anesthesia and Reanimation Intensive Care Unit of the Republic of Turkey Ministry of Health Aydın Provincial Health Directorate Nazilli State Hospital Patients will be divided into a total of 5 groups 4 experimental and 1 control group The groups to which 1 chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid solutions are applied will constitute the experimental group and the patients who receive oral care with 012 chlorhexidine gluconate which is routinely applied in the clinic will constitute the control group Patients will be given oral care by the nurse with determined solutions chlorhexidine gluconate sodium bicarbonate ozonated water and hypochlorous acid 4 times a day according to the oral care protocol and the oral mucosa of all patient groups will be evaluated every morning for 7 days A deep tracheal aspirate sample will be taken and a chest x-ray will be taken on the first and seventh days after hospitalization of intubated patients The development of VAP in patients will be evaluated with the clinical pulmonary infection score
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None