Ignite Creation Date:
2024-05-06 @ 7:42 PM
Last Modification Date:
2024-10-26 @ 3:12 PM
Study NCT ID:
NCT06102616
Status:
COMPLETED
Last Update Posted:
2023-11-28
First Post:
2023-10-22
Brief Title:
Osteocalcin Level in Gingival Clavicular Fluid During Canine Retraction in Periodontal Compromised Patients
Sponsor:
Faculty of Dental Medicine for Girls
Organization:
Faculty of Dental Medicine for Girls
Study Overview
Official Title:
Osteocalcin Level in Gingival Clavicular Fluid During Canine Retraction in Periodontal Compromised Patients
Status:
COMPLETED
Status Verified Date:
2023-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Osteocalcin levels can be measured Gingival crevicular fluid GCF Changes in osteocalcin levels can provide important information about the status of bone metabolism and bone remodeling The levels of this markers in GCF can provide information about the status of bone remodeling in the surrounding bone tissue in periodontal affected teeth
Detailed Description:
Osteocalcin levels can be measured using a blood test or by analyzing the levels of osteocalcin in urine or saliva Changes in osteocalcin levels can provide important information about the status of bone metabolism and bone remodeling Osteocalcin has been found to be present in Gingival crevicular fluid GCF along with other bone metabolism markers such as alkaline phosphatase and tartrate-resistant acid phosphatase The levels of these markers in GCF can provide information about the status of bone remodeling in the surrounding bone tissue Orthodontic tooth movement is influenced by the remodelling ability of surrounding bone and soft tissue such as PDL and gingiva Bone remodelling occurs in coordination requiring coupling of bone formation after resorption Orthodontic force induces an aseptic inflammatory response involving cytokines and chemokines Increased levels of osteocalcin in body fluids indicate abnormal bone turnover activity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None