Ignite Creation Date:
2024-05-06 @ 7:42 PM
Last Modification Date:
2024-10-26 @ 3:11 PM
Study NCT ID:
NCT06100471
Status:
ENROLLING_BY_INVITATION
Last Update Posted:
2024-02-20
First Post:
2023-10-13
Brief Title:
Evaluation of Genetic Signature in Endometriosis Disease by Non Invasive Sampling
Sponsor:
Eurofins Genoma
Organization:
Eurofins Genoma
Study Overview
Official Title:
Evaluation of Genetic Signature in Endometriosis Disease by Non Invasive Sampling
Status:
ENROLLING_BY_INVITATION
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
niEndometriosi
Brief Summary:
Endometriosis is a disease that affects 10-15 of the general population and 50 of infertile women It is characterized by the presence of endometrial tissue outside the uterine cavity Endometriosis can lead to infertility by interfering through endocrine and mechanical alterations on the function of the ovaries fallopian tubes and uterus The aim of the study is to define the differential expression of a cluster of RNAs tissue driven for the identification of an RNA profile in saliva specific for endometriosis This study focuses on the expression of genes involved in the control and regulation of apoptosis cell survival metabolism cell adhesion and invasion angiogenesis inflammation and estrogen receptor expression levels
Detailed Description:
Retrospective selection based on anamnestic criteria of 50 patients with diagnosed endometriotic adnexal pathology case CA 50 patients with non-endometriotic adnexal pathology control CO and 50 patients with no gynecological pathology not undergoing surgery analytical control
The study involves collecting a saliva sample from all patients involved in the study and performing a biopsy from both patients with endometriotic adnexal pathology CA and patients with non-endometriotic adnexal pathology CO
The study involves collecting a saliva sample from all patients involved in the study and performing a biopsy from both patients with endometriotic adnexal pathology CA and patients with non-endometriotic adnexal pathology CO
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None