Ignite Creation Date:
2024-05-06 @ 7:42 PM
Last Modification Date:
2024-10-26 @ 3:12 PM
Study NCT ID:
NCT06101537
Status:
RECRUITING
Last Update Posted:
2024-04-22
First Post:
2023-10-18
Brief Title:
Correlation Patterns of Brain Temperature-Pressure in Acute Brain Injury
Sponsor:
Beijing Tiantan Hospital
Organization:
Beijing Tiantan Hospital
Study Overview
Official Title:
Correlation Patterns of Brain Temperature-Pressure in Acute Brain Injurya Multicenter Prospective Cohort Study MERCURY
Status:
RECRUITING
Status Verified Date:
2024-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MERCURY
Brief Summary:
The goal of this prospective multicenter observational cohort trail is to explore the pattern of brain temperature-brain pressure association in acute brain injury and to clarify its predictive value for prognosis and neurological function 30 days after acute brain injury
Detailed Description:
Temperature abnormalities have long been recognized as signs of disease Brain temperature as part of body temperature reflects body temperature and brain metabolism during physiologic states There is growing evidence that brain cell function is unequivocally temperature dependent and that brain temperature after brain injury cannot be reliably predicted by core body temperature Brain temperature is therefore increasingly becoming an important alternative to brain pressure enabling patients with a variety of brain injuries to benefit from continuous brain temperature monitoring Meanwhile the correlation between intracranial pressure which is currently the most widely used indicator in clinical practice and brain temperature in patients with acute brain injury remains unelucidated Whether the correlation between brain temperature and intracranial pressure has certain patterns and rhythms that can indirectly reflect the brain function of patients under the condition of injury and have a predictive value for clinical outcomes is the main research objective of this study It is hoped that the present study will explore the correlation between brain temperature and brain pressure and the pattern of the correlation as well as its impact on clinical prognosis It provides a more precise target for intervention to further improve the prognosis of patients with acute brain injury
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None