Ignite Creation Date:
2024-05-06 @ 7:40 PM
Last Modification Date:
2024-10-26 @ 3:11 PM
Study NCT ID:
NCT06094023
Status:
RECRUITING
Last Update Posted:
2023-10-23
First Post:
2023-10-03
Brief Title:
Dietary Intake of Folic Acid and Vitamin B12 Among Teenage Girls - Validation of Food Frequency Questionnaire
Sponsor:
University Ghent
Organization:
University Ghent
Study Overview
Official Title:
Development and Validation of Food Frequency Questionnaire to Assess the Dietary Intake of Folic Acid and Vitamin B12 Among Teenage Girls in South Ethiopia
Status:
RECRUITING
Status Verified Date:
2023-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Folate and vitamin B12 deficiencies are associated with various health issues including anemia cardiovascular disease depression and birth defects Accurate and objective estimates of dietary intake are necessary to assess any effects of nutritional status in epidemiologic studies This study aims to develop and validate a three-month semi-quantitative food frequency questionnaire for the assessment of dietary intake of folic acid and vitamin B12 against fourtwo multiple-pass 24-hr dietary recall among teenage girls in South Ethiopia
Detailed Description:
Folic acid and vitamin B12 play an interdependent role in key cellular processes namely deoxyribonucleic acid synthesis cell division red blood cell formation and nervous system myelination Folic acid is an essential nutrient in the growth and development of the cerebral cortex It promotes the thickness of the cerebral cortex which is directly proportional to the intelligence quotient the neurocognitive and psychological development of the child Both folate and vitamin B12 participate in the conversion of homocysteine to methionine such that a deficiency in either vitamin will result in elevated serum concentrations of homocysteine where high levels of serum homocysteine are associated with an increased risk for depression Deficiencies in folate and vitamin B12 have been shown to delay growth spurt and pubertal growth during adolescence Some studies also showed that there is an association between overweight and obesity with lower serum vitamin B12 and folate levels
In research there are several challenges in the accurate assessment of diet and nutrition In the Ethiopian context there is no tool that specifically assesses dietary intake of folic acid and vitamin B12 in adolescents In this project reliable dietary assessment tools for assessing dietary intake of folic acid and vitamin B12 will be developed and validated for future use as an unbiased reference measure The dietary validation study will start by conducting a food frequency questionnaire FFQ The FFQ will consider the recall time frame of the previous three months assuming that the consumption patterns for folate and vitamin B12-rich foods of participants over a three-month period can be considered as their usual food intake The FFQ will be administered to the selected study participants four times at the beginning of the validation study after 3 and 6 months and at 9 months the end of the study The same participants will be also asked to complete two 24-hour food recalls every three months in a nine-month period The first 24-hour recall questionnaires will be collected at least one week after the first FFQ and one within the 3-month period considering one weekday and one weekend day A total of eight 24-hour food recalls and four FFQs will be collected
Study objective
The objective of this sub study is to develop and validate a FFQ that can be used to assess the dietary intake of folic acid and vitamin B12 among teenage girls who reside in rural communities of Arba Minch Health and Demographic Surveillance Sites AM-HDSS South Ethiopia
In research there are several challenges in the accurate assessment of diet and nutrition In the Ethiopian context there is no tool that specifically assesses dietary intake of folic acid and vitamin B12 in adolescents In this project reliable dietary assessment tools for assessing dietary intake of folic acid and vitamin B12 will be developed and validated for future use as an unbiased reference measure The dietary validation study will start by conducting a food frequency questionnaire FFQ The FFQ will consider the recall time frame of the previous three months assuming that the consumption patterns for folate and vitamin B12-rich foods of participants over a three-month period can be considered as their usual food intake The FFQ will be administered to the selected study participants four times at the beginning of the validation study after 3 and 6 months and at 9 months the end of the study The same participants will be also asked to complete two 24-hour food recalls every three months in a nine-month period The first 24-hour recall questionnaires will be collected at least one week after the first FFQ and one within the 3-month period considering one weekday and one weekend day A total of eight 24-hour food recalls and four FFQs will be collected
Study objective
The objective of this sub study is to develop and validate a FFQ that can be used to assess the dietary intake of folic acid and vitamin B12 among teenage girls who reside in rural communities of Arba Minch Health and Demographic Surveillance Sites AM-HDSS South Ethiopia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None