Ignite Creation Date:
2024-05-06 @ 7:40 PM
Last Modification Date:
2024-10-26 @ 3:11 PM
Study NCT ID:
NCT06094452
Status:
COMPLETED
Last Update Posted:
2023-10-23
First Post:
2023-10-04
Brief Title:
Effects of 24-week Computerized Cognitive Training in Patients With MCI and AD
Sponsor:
Chongqing Medical University
Organization:
Chongqing Medical University
Study Overview
Official Title:
Effects of 24-week Computerized Cognitive Training on Microbiota-gut-brain Axis in Patients With Mild Cognitive Impairment and Mild Alzheimers Disease a Randomized Controlled Trial
Status:
COMPLETED
Status Verified Date:
2023-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to testify multi-domain effects of computerized cognitive training in patients with mild cognitive impairment and mild Alzheimers disease through multi-dimensional evaluation
Detailed Description:
This study aimed to elucidate the neural process enhancement and remodulation in gut microbes resulting from older adults with MCI and mild AD in a randomized controlled trial of a 24-week computerized cognitive training CCT program
After recruitment and baseline assessments pairs of participants with MCI and mild AD would be randomly allocated into the corresponding subgroup Participants in CCT group will receive a computerized multidomain cognitive training program www66naocom and will be required to complete at least 30 minutes of training per day 3 cycle of 5 2-min tasks 5 days a week for 24 weeks Adherence to the intervention will be supervised by an independent researcher The number of training days and training hours per day will be recorded Patients in control group received treatment as usual TAU for 24 weeks The neuropsychological measures will be performed at baseline follow-up at 4 weeks 12 weeks and 24 weeks functional Near-Infrared Spectroscopy fNIRS data and fecal samples will collected at baseline and 24 weeks
After recruitment and baseline assessments pairs of participants with MCI and mild AD would be randomly allocated into the corresponding subgroup Participants in CCT group will receive a computerized multidomain cognitive training program www66naocom and will be required to complete at least 30 minutes of training per day 3 cycle of 5 2-min tasks 5 days a week for 24 weeks Adherence to the intervention will be supervised by an independent researcher The number of training days and training hours per day will be recorded Patients in control group received treatment as usual TAU for 24 weeks The neuropsychological measures will be performed at baseline follow-up at 4 weeks 12 weeks and 24 weeks functional Near-Infrared Spectroscopy fNIRS data and fecal samples will collected at baseline and 24 weeks
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None