Ignite Creation Date:
2024-05-06 @ 7:38 PM
Last Modification Date:
2024-10-26 @ 3:10 PM
Study NCT ID:
NCT06074029
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2024-02-08
First Post:
2023-09-24
Brief Title:
Exploratory Study on the Therapeutic Effect Prediction Model of Advanced BTC Immunotherapy
Sponsor:
Peking Union Medical College Hospital
Organization:
Peking Union Medical College Hospital
Study Overview
Official Title:
Exploratory Study on the Therapeutic Effect Prediction Model of Immune Checkpoint Inhibitors for Advanced Biliary Tract Cancer
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
1 Establish a predictive model for the efficacy of immune checkpoint inhibitors ICI in Chinese patients with biliary tract cancers By analyzing the dynamic changes of circulating tumor DNA ctDNA and other clinical and pathological features before and after ICI treatment in a cohort of patients with biliary tract tumors a predictive model can be established to evaluate the efficacy of ICI treatment in the early stages or even before treatment serving as a reliable tool for selecting patients who are likely to benefit from ICI treatment
2 Investigate the clinical features of populations that benefit from different immune combination therapies By comparing the differences and enrichment of mutations between patients receiving different treatment regimens and if patients have sufficient pre-treatment tissue further comparisons of differentially expressed genes and pathways may be made
2 Investigate the clinical features of populations that benefit from different immune combination therapies By comparing the differences and enrichment of mutations between patients receiving different treatment regimens and if patients have sufficient pre-treatment tissue further comparisons of differentially expressed genes and pathways may be made
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None