Ignite Creation Date:
2024-05-06 @ 7:36 PM
Last Modification Date:
2024-10-26 @ 3:10 PM
Study NCT ID:
NCT06069986
Status:
RECRUITING
Last Update Posted:
2023-10-06
First Post:
2023-09-13
Brief Title:
On-pump Versus Off-pump Coronary Artery Bypass Grafting Short Term Outcomes Sohag Experience
Sponsor:
Sohag University
Organization:
Sohag University
Study Overview
Official Title:
On-pump Versus Off-pump Coronary Artery Bypass Grafting Short Term Outcomes Sohag Experience
Status:
RECRUITING
Status Verified Date:
2023-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Coronary artery disease CAD and its sequlae such as myocardial infarction arrhythmia and heart failure are among the leading causes of death around the world the durable role of coronary artery bypass grafting CABG in the treatment of CAD has long been shown
Coronary artery bypass grafting CABG is a commonly performed surgical procedure for patients with coronary artery disease CAD CABG can be performed using either the on-pump or off-pump technique each with its own advantages and limitations
On-pump CABG involves the use of CPB which as agold standard for surgical coronary revascularization has led toexcellent results in mortality and complications On-pump CABG allows the surgeon to temporarily stop the heart and provide perfusion and oxygenation to the body This technique provides a bloodless and motionless operative field allowing for precise graft anastomosis However the use of CPB is associated with deleterious effects as systemic inflammatory response hemodilution and organ dysfunction as dysrhythmia and neurocognitive problems These factors may adversely affect patients lives specially those with impaired EF who already have compromised cardiovascular function
Another technique for CABG is on-pump beating heart CABG ONBH-CABG surgery that is relatively novel hybrid approach to coronary artery grafting which aims to stabilize hemodynamic parameters during the operative period This has specific benefits such as reduced preload alongside the afterload which decreases the oxygen demand of the myocardial tissue
Coronary artery bypass grafting CABG is a commonly performed surgical procedure for patients with coronary artery disease CAD CABG can be performed using either the on-pump or off-pump technique each with its own advantages and limitations
On-pump CABG involves the use of CPB which as agold standard for surgical coronary revascularization has led toexcellent results in mortality and complications On-pump CABG allows the surgeon to temporarily stop the heart and provide perfusion and oxygenation to the body This technique provides a bloodless and motionless operative field allowing for precise graft anastomosis However the use of CPB is associated with deleterious effects as systemic inflammatory response hemodilution and organ dysfunction as dysrhythmia and neurocognitive problems These factors may adversely affect patients lives specially those with impaired EF who already have compromised cardiovascular function
Another technique for CABG is on-pump beating heart CABG ONBH-CABG surgery that is relatively novel hybrid approach to coronary artery grafting which aims to stabilize hemodynamic parameters during the operative period This has specific benefits such as reduced preload alongside the afterload which decreases the oxygen demand of the myocardial tissue
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None