Ignite Creation Date:
2024-05-06 @ 7:36 PM
Last Modification Date:
2024-10-26 @ 3:09 PM
Study NCT ID:
NCT06063915
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-10-03
First Post:
2023-07-28
Brief Title:
Isoinertial Rehabilitation in Recovering Hamstring Strength Following Surgical Anterior Cruciate Ligament Reconstruction
Sponsor:
Università degli studi di Roma Foro Italico
Organization:
Università degli studi di Roma Foro Italico
Study Overview
Official Title:
Efficacy of Isoinertial Rehabilitation in Recovering Hamstring Strength Following Surgical Anterior Cruciate Ligament Reconstruction a Randomized Controlled Trial
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The present experimental study aims to evaluate the effectiveness and tolerability of isoinertial strength training of the hamstrings using machines in patients with ACL-R during the intermediate post-intervention phases
Detailed Description:
A proper post-operative rehabilitation program is essential for a positive outcome after anterior cruciate ligament ACL reconstruction surgery a procedure known to cause morpho-functional issues in the short medium and long term in individuals who undergo it Generally after an initial rehabilitation phase focused on protecting the healing process of the new ligament and regaining range of motion the rehabilitation path focuses on muscular strengthening and neuromuscular control of both lower limbs It has been demonstrated that deficits in extensor and flexor muscle strength as well as their strength ratios increase the risk of re-injury Specifically in athletes the rate of recurrence defined as a new injury to the same or opposite side ACL is considerably high
High-intensity resistance training of the operated limb has often been contraindicated in the early post-operative period as it was considered detrimental to the new ligament joint cartilage and surrounding soft tissues However recent studies suggest that the early application of progressive eccentric-focused exercises even with high loads can be safely used to increase muscle volume and strength levels in individuals undergoing ACL reconstruction ACL-R Therefore eccentric reinforcement can be a valid alternative to traditional concentric work for improving lower limb muscle strength after ACL-R
Recently it has been demonstrated that strength training using isoinertial machines in healthy individuals leads to positive chronic adaptations in terms of strength recovery power and functional capacities such as sprinting change of direction and agility Isoinertial training allows for exercises in both closed and open kinetic chains as well as multiplanar motor activities The combination of concentric phases with subsequent eccentric overload allows for the development of high levels of strength and power with low energy cost promotes intermuscular coordination preferentially recruits motor units with high activation thresholds and increases cortical activity Increased muscle activation particularly during eccentric muscle actions indicates a higher mechanical load and a greater training stimulus leading to better and earlier protein synthesis and subsequent muscle hypertrophy compared to traditional resistance training Furthermore the metabolic cost required for an eccentric contraction is about a quarter of that for a concentric contraction at the same external load Therefore at the same contraction velocity eccentric contractions allow for a higher force expression
While the use of isoinertial equipment is well-established in healthy individuals scientific evidence regarding its use in rehabilitation protocols is currently limited The use of eccentric overload in addition to improving parameters related to muscle strength and power seems to promote tendon remodeling due to an increased production of fibroblasts and collagen generated by the higher mechanical load compared to traditional concentric exercise In lower limb pathologies isoinertial rehabilitation following injury can be a valid alternative to traditional strength training for the development of muscle hypertrophy and function However specific studies investigating the effects of isoinertial rehabilitation in the intermediate stages of recovery following ACL-R and monitoring the tolerability of the treatment are currently lacking
High-intensity resistance training of the operated limb has often been contraindicated in the early post-operative period as it was considered detrimental to the new ligament joint cartilage and surrounding soft tissues However recent studies suggest that the early application of progressive eccentric-focused exercises even with high loads can be safely used to increase muscle volume and strength levels in individuals undergoing ACL reconstruction ACL-R Therefore eccentric reinforcement can be a valid alternative to traditional concentric work for improving lower limb muscle strength after ACL-R
Recently it has been demonstrated that strength training using isoinertial machines in healthy individuals leads to positive chronic adaptations in terms of strength recovery power and functional capacities such as sprinting change of direction and agility Isoinertial training allows for exercises in both closed and open kinetic chains as well as multiplanar motor activities The combination of concentric phases with subsequent eccentric overload allows for the development of high levels of strength and power with low energy cost promotes intermuscular coordination preferentially recruits motor units with high activation thresholds and increases cortical activity Increased muscle activation particularly during eccentric muscle actions indicates a higher mechanical load and a greater training stimulus leading to better and earlier protein synthesis and subsequent muscle hypertrophy compared to traditional resistance training Furthermore the metabolic cost required for an eccentric contraction is about a quarter of that for a concentric contraction at the same external load Therefore at the same contraction velocity eccentric contractions allow for a higher force expression
While the use of isoinertial equipment is well-established in healthy individuals scientific evidence regarding its use in rehabilitation protocols is currently limited The use of eccentric overload in addition to improving parameters related to muscle strength and power seems to promote tendon remodeling due to an increased production of fibroblasts and collagen generated by the higher mechanical load compared to traditional concentric exercise In lower limb pathologies isoinertial rehabilitation following injury can be a valid alternative to traditional strength training for the development of muscle hypertrophy and function However specific studies investigating the effects of isoinertial rehabilitation in the intermediate stages of recovery following ACL-R and monitoring the tolerability of the treatment are currently lacking
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None