Ignite Creation Date:
2024-05-06 @ 7:35 PM
Last Modification Date:
2024-10-26 @ 3:10 PM
Study NCT ID:
NCT06067399
Status:
RECRUITING
Last Update Posted:
2024-04-02
First Post:
2023-09-21
Brief Title:
Relationship Between Red Cell Distribution Width RDW and HbA1C in Patients With Type 2 Diabetes Mellitus After Glycemic Control
Sponsor:
New Valley University
Organization:
New Valley University
Study Overview
Official Title:
Relationship Between Red Cell Distribution Width RDW and HbA1C in Patients With Type 2 Diabetes Mellitus After Glycemic Control
Status:
RECRUITING
Status Verified Date:
2024-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Diabetes mellitus DM is an epidemic disease with approximately 463 million persons diagnosed with it Of those 90 are patients with type 2 DM T2DM Some estimates indicate that 700 million cases of DM will be reported in 2045 T2DM develops due to insulin resistance leading to reduced insulin secretion DM has a number of associated complications such as nephropathy neuropathy and cardiovascular disease
Detailed Description:
The health status of normal individuals and patients with various diseases is commonly monitored using the complete blood count CBC In patients with T2DM the CBC can be used as a follow-up test which will help in reducing complications associated with the disease Some CBC parameters have also been used as prognostic markers for T2DM One of these markers is the red cell distribution width RDW which measures the variability in the sizes of red blood cells RBCs and is considered an indicator of their heterogeneity The evidence associating RDW with a higher risk of mortality has been expanding since the initial report of its prognostic utility in heart failure patients Multiple studies have shown that elevated RDW values are associated with many human diseases such as cancer cardiovascular disease and diabetes and are also associated with disease activity or complications of diseases The RDW can be used diagnostically in patients with T2DM and other illnesses as patients with T2DM frequently show alterations in various hematological properties including changes in the structure metabolism and function of blood cells These alterations can be caused by different factors such as excessive levels of reactive oxygen species ROS leading eventually to oxidative stress and the dysfunction of RBCs
The relationship between RDW and T2DM has been studied for several years and there are no consistent results
The relationship between RDW and T2DM has been studied for several years and there are no consistent results
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None