Ignite Creation Date:
2024-05-06 @ 7:35 PM
Last Modification Date:
2024-10-26 @ 3:10 PM
Study NCT ID:
NCT06067815
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-10-05
First Post:
2023-09-28
Brief Title:
Assessment of Right Ventricular Function in Patients With Severe Mitral Stenosis Before and After Balloon Mitral Valvuloplasty
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Assessment of Right Ventricular Function in Patient With Severe Mitral Stenosis Before and After Balloon Mitral Valvuloplasty
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To detect short-term impacts of successful balloon mitral valvuloplasty on right ventricular function
Detailed Description:
In patients with mitral valve stenosis right ventricular failure may develop either by the rheumatic process directly or through hemodynamic alterations resulting from pulmonary vascular changes
Right ventricular RV function plays an important role in development of clinical symptoms and prognosis in patients with mitral stenosis MSThis is primarily affected by hemodynamic effects on RV due to pulmonary hypertensionPH
In the last two decades Percutaneous Transluminal Mitral Commissurotomy PTMC has become the treatment of choice for patients with symptomatic rheumatic MS Using this methodMitral Valve Area MVA can be increased which can improve the hemodynamic and clinical features of patients with MS
RV functional assessment is difficult and not done routinely because of its complex anatomy and high load dependence
Different modalitis are used to assess RV function as Tissue Doppler and two-dimensional 2D speckle tracking method has been used to quantify strain for assessment Myocardial strain is a measure of tissue deformation which is expressed as a percentage change
Right ventricular RV function plays an important role in development of clinical symptoms and prognosis in patients with mitral stenosis MSThis is primarily affected by hemodynamic effects on RV due to pulmonary hypertensionPH
In the last two decades Percutaneous Transluminal Mitral Commissurotomy PTMC has become the treatment of choice for patients with symptomatic rheumatic MS Using this methodMitral Valve Area MVA can be increased which can improve the hemodynamic and clinical features of patients with MS
RV functional assessment is difficult and not done routinely because of its complex anatomy and high load dependence
Different modalitis are used to assess RV function as Tissue Doppler and two-dimensional 2D speckle tracking method has been used to quantify strain for assessment Myocardial strain is a measure of tissue deformation which is expressed as a percentage change
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None