Ignite Creation Date:
2024-05-06 @ 7:34 PM
Last Modification Date:
2024-10-26 @ 3:09 PM
Study NCT ID:
NCT06055660
Status:
COMPLETED
Last Update Posted:
2023-09-28
First Post:
2023-09-20
Brief Title:
Moesin Expression in Clear Cell Renal Cell Carcinoma
Sponsor:
Sohag University
Organization:
Sohag University
Study Overview
Official Title:
Expression and Distribution of Membrane-Organizing Extension Spike Protein Moesin MSN is Associated With Epithelial-Mesenchymal Transition in Clear Cell Renal Cell Carcinoma
Status:
COMPLETED
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Renal cell carcinoma RCC is the most frequently occurring primary renal neoplasm There are several histological variants of RCC that are associated with variable prognostic outcomes Epithelial-mesenchymal transition EMT is a phenomenon in which the epithelial cells acquire some mesenchymal criteria as enhanced invasive potential There are several cell surface molecules that are implicated in EMT Moesin is one of these molecules that is involved in EMT which is associated with enhanced invasive potential and poor prognosis Targeting Moesin by novel therapeutic agents may prevent EMT and improve prognosis of patients with RCC
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None