Ignite Creation Date:
2024-05-05 @ 11:21 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00007046
Status:
COMPLETED
Last Update Posted:
2005-06-24
First Post:
2000-12-06
Brief Title:
Genetic Study of Patients and Families With Diaphyseal Medullary Stenosis With Malignant Fibrous Histiocytoma of the Bone
Sponsor:
National Center for Research Resources NCRR
Organization:
National Center for Research Resources NCRR
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2003-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
OBJECTIVES I Identify and characterize the gene causing diaphyseal medullary stenosis with malignant fibrous histiocytoma of the bone
II Determine the clinical manifestations of this disease in these patients
II Determine the clinical manifestations of this disease in these patients
Detailed Description:
PROTOCOL OUTLINE Blood samples are obtained from affected individuals and their family members after genetic counseling Genetic linkage analysis is performed on these blood samples Unaffected individuals undergo x-rays and technetium bone scans to detect the presence of bone disease Affected individuals undergo bone densitometry MRI studies thallium scans ophthalmologic examination electrocardiogram echocardiogram and skin biopsies
Affected family members identified after radiologic studies receive additional genetic counseling
Affected family members identified after radiologic studies receive additional genetic counseling
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| MTS-GCO-97-304HG | None | None | None |
| MTS-97-304-0001-HG | None | None | None |