Ignite Creation Date:
2024-05-06 @ 7:32 PM
Last Modification Date:
2024-10-26 @ 3:09 PM
Study NCT ID:
NCT06048549
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-09-21
First Post:
2023-09-16
Brief Title:
The Effect of Obesity in COPD Mechanically Ventilated Patients
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Effect Of Obesity on The Outcome Of Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Study the relationship between the body mass index and duration of mechanical ventilation complications in mechanically ventilated COPD patients
Study the effect of obesity on mortality rate of COPD mechanically ventilated patients
Determine prevalence of obesity in mechanically ventilated COPD patients
Study the effect of obesity on mortality rate of COPD mechanically ventilated patients
Determine prevalence of obesity in mechanically ventilated COPD patients
Detailed Description:
Obesity has become a global epidemic with prevalence rising both in developed and developing countries The percentage of patients with obesity in the intensive care unit ICU can be expected to increase concomitantly or even more since obesity increases the risk for a more severe disease course with more need for ICU admission and mechanical ventilation
Obesity especially abdominal obesity android fat distribution and severe obesity results in altered respiratory anatomy and physiology and therefore complicated airway management and adapted ventilator settings during mechanical ventilation Obesity appears to be associated with an increased risk of acute respiratory distress syndrome ARDS and infection mainly pneumonia probably related to an imbalanced production of adipokines In ventilated patients obesity increases ICU length of stay and the duration of mechanical ventilation
Obesity is relatively common among individuals with COPD corresponding to 20-35 of patients with COPD Increasing evidence suggests that obesity is a risk factor for impaired quality of life exercise intolerance and suboptimal disease control in COPD
Obesity especially abdominal obesity android fat distribution and severe obesity results in altered respiratory anatomy and physiology and therefore complicated airway management and adapted ventilator settings during mechanical ventilation Obesity appears to be associated with an increased risk of acute respiratory distress syndrome ARDS and infection mainly pneumonia probably related to an imbalanced production of adipokines In ventilated patients obesity increases ICU length of stay and the duration of mechanical ventilation
Obesity is relatively common among individuals with COPD corresponding to 20-35 of patients with COPD Increasing evidence suggests that obesity is a risk factor for impaired quality of life exercise intolerance and suboptimal disease control in COPD
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None