Ignite Creation Date:
2024-05-06 @ 7:31 PM
Last Modification Date:
2024-10-26 @ 3:07 PM
Study NCT ID:
NCT06030479
Status:
RECRUITING
Last Update Posted:
2023-09-11
First Post:
2023-08-28
Brief Title:
Topical Adrenaline Versus Warm Saline Solution for Minimizing Intraperitoneal Bleeding During Caesarian Delivery for Placenta Previa Accreta Spectrum PAS
Sponsor:
Cairo University
Organization:
Cairo University
Study Overview
Official Title:
Topical Adrenaline Versus Warm Saline Solution for Minimizing Intraperitoneal Bleeding During Caesarian Delivery for Placenta Previa Accreta Spectrum PAS A Randomized Controlled Study
Status:
RECRUITING
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Placenta accreta spectrum PAS encompassing the terms placenta accreta increta and percreta abnormally invasive placenta morbidly adherent placenta and invasive placentation is a leading cause of life-threatening obstetric haemorrage Currently more than 90 of women diagnosed with PAS also have a placenta praevia and the combination of both conditions leads to high maternal morbidity and mortality due to massive haemorrhage at the time of birth Maternal mortality of placenta praevia with percreta has been reported to be as high as 7 of cases
Adrenaline has also been demonstrated to be a reasonable hemostatic agent because of its low cost low risk powerful vasoconstrictor and platelet aggregation Topical use of adrenaline is an effective and reasonable hemostatic agent in tonsillectomy
Adrenaline has also been demonstrated to be a reasonable hemostatic agent because of its low cost low risk powerful vasoconstrictor and platelet aggregation Topical use of adrenaline is an effective and reasonable hemostatic agent in tonsillectomy
Detailed Description:
Population of study A total of 84 pregnant patients with placenta previa Accreta spectrum
Study location Obstetrics and Gynecology Kasr Al-Ainy Hospital Faculty of Medicine Cairo University
This is a randomized controlled trial including a total number of 84 patients representing study group randomized in 2 equal groups using computer generated randomization sheet on Medcalc
Group A Topical adrenaline group n42
Group B Warm saline Group control n42
The aim of the study is to evaluate the efficacy of topical adrenaline for decreasing intraperitoneal bleeding during caesarian section for placenta previa Accreta spectrum PAS
Study location Obstetrics and Gynecology Kasr Al-Ainy Hospital Faculty of Medicine Cairo University
This is a randomized controlled trial including a total number of 84 patients representing study group randomized in 2 equal groups using computer generated randomization sheet on Medcalc
Group A Topical adrenaline group n42
Group B Warm saline Group control n42
The aim of the study is to evaluate the efficacy of topical adrenaline for decreasing intraperitoneal bleeding during caesarian section for placenta previa Accreta spectrum PAS
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None