Ignite Creation Date:
2024-05-06 @ 7:30 PM
Last Modification Date:
2024-10-26 @ 3:07 PM
Study NCT ID:
NCT06030596
Status:
RECRUITING
Last Update Posted:
2023-09-11
First Post:
2023-08-31
Brief Title:
SPECT Myocardial Blood Flow Quantification for Diagnosis of Ischemic Heart Disease Determined by Fraction Flow Reserve
Sponsor:
China National Center for Cardiovascular Diseases
Organization:
China National Center for Cardiovascular Diseases
Study Overview
Official Title:
SPECT Myocardial Blood Flow Quantification for Diagnosis of Ischemic Heart Disease Determined by Fraction Flow Reserve
Status:
RECRUITING
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Recent evidences have demonstrated improved diagnostic accuracy for detecting coronary artery disease CAD when myocardial blood flow MBF is quantified in absolute terms using single photon emission tomography SPECT compared to conventional myocardial perfusion imaging MPI However there are no uniformly accepted cutoff values of MBF and MFR derived from SPECT for diagnosing hemodynamically significant CAD Particularly the diagnostic performance for quantitative SPECT has not been validated using fractional flow reserve FFR The aim of this prospective study is to determine optimal cutoff values of absolute MBF and MFR derived from NaI Tl-based SPECT and to evaluate the diagnostic efficacy of this quantitative technology utilizing invasive coronary angiography ICA in combination with FFR results as the reference standard in patients with suspected or known CAD
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None