Ignite Creation Date:
2024-05-06 @ 7:29 PM
Last Modification Date:
2024-10-26 @ 3:08 PM
Study NCT ID:
NCT06031909
Status:
RECRUITING
Last Update Posted:
2023-09-11
First Post:
2023-08-30
Brief Title:
Multimodal Assessment of Frailty in Acute Stroke Patients
Sponsor:
University of Giessen
Organization:
University of Giessen
Study Overview
Official Title:
Multimodal Assessment of Frailty in Acute Stroke Patients Treated at a Certified Stroke-unit
Status:
RECRUITING
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MAFASP
Brief Summary:
The goal of this study is to investigate the influence of frailty on clinical and stroke characteristics treatment and outcomes in patients with acute stroke
The main questions it aims to answer are
1 How prevalent is frailty in patients with stroke
2 Which impairments eg undernutrion impaired mobility laboratory markers contribute to frailty
3 Is the outcome of frail patients worse than those without
4 Are in-hospital complications more frequent in frail patients than those without
The main questions it aims to answer are
1 How prevalent is frailty in patients with stroke
2 Which impairments eg undernutrion impaired mobility laboratory markers contribute to frailty
3 Is the outcome of frail patients worse than those without
4 Are in-hospital complications more frequent in frail patients than those without
Detailed Description:
Stroke is one of the most common causes of disability and mortality worldwide A recognized complication in stroke patients is frailty which is associated with increased costs poorer prognosis and higher mortality rates However there is currently no uniform definition or diagnostic criteria for frailty in stroke patients and there is a need for standardized frailty assessments in this patient population
The aim of this study is to determine the prevalence of frailty in stroke patients at the Stroke Unit of the University Hospital Giessen and to analyze the associated characteristics and impacts on clinical outcomes A multimodal frailty assessment will be conducted to capture a wide range of frailty features and investigate their significance The study includes all stroke patients admitted to the certified stroke- unit of the University Hospital Giessen within a 3-month period There are no inclusion criteria related to age gender or type of stroke
The multimodal frailty assessment encompasses determining appropriate blood values eg CRP albumin assessing muscle strengthmass through handheld dynamometry and sonographic muscle diameter utilizing scores like the Clinical Frailty Scale CFS and the Groningen Frailty Indicator GFI evaluating nutritional status BMI collecting image-based frailty data eg sarcopenia cerebral white matter lesions lacunar strokes brain atrophy and conducting suitable one-year follow-ups Additionally demographic and clinical data such as age gender type of stroke and treatment details will be recorded
The primary outcome is the prevalence of frailty among stroke patients Secondary outcomes include the characteristics and impacts of frailty in stroke patients including correlations between various frailty features and clinical outcomes such as length of hospital stay mortality and functional outcome
The aim of this study is to determine the prevalence of frailty in stroke patients at the Stroke Unit of the University Hospital Giessen and to analyze the associated characteristics and impacts on clinical outcomes A multimodal frailty assessment will be conducted to capture a wide range of frailty features and investigate their significance The study includes all stroke patients admitted to the certified stroke- unit of the University Hospital Giessen within a 3-month period There are no inclusion criteria related to age gender or type of stroke
The multimodal frailty assessment encompasses determining appropriate blood values eg CRP albumin assessing muscle strengthmass through handheld dynamometry and sonographic muscle diameter utilizing scores like the Clinical Frailty Scale CFS and the Groningen Frailty Indicator GFI evaluating nutritional status BMI collecting image-based frailty data eg sarcopenia cerebral white matter lesions lacunar strokes brain atrophy and conducting suitable one-year follow-ups Additionally demographic and clinical data such as age gender type of stroke and treatment details will be recorded
The primary outcome is the prevalence of frailty among stroke patients Secondary outcomes include the characteristics and impacts of frailty in stroke patients including correlations between various frailty features and clinical outcomes such as length of hospital stay mortality and functional outcome
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None