Ignite Creation Date:
2024-05-06 @ 7:29 PM
Last Modification Date:
2024-10-26 @ 3:07 PM
Study NCT ID:
NCT06024733
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2023-10-10
First Post:
2023-08-23
Brief Title:
Intravenous Anesthesia by Targeted Controlled Infusion Versus Inhalational Anesthesia on the Surgical Stress Response
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Effect of Total Intravenous Anesthesia by Targeted Controlled Infusion on Surgical Stress Response Compared to Inhalational Anesthesia
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study aims to compare the effect of total Intravenous anesthesia Target-controlled infusion TIVA-TCI with inhalational anesthesia on stress response
Detailed Description:
Target-controlled infusion TCI techniques have been used to induce and maintain general anesthesia or to provide computer-assisted personalized sedation Target-controlled infusion TCI systems are computer-assisted IV infusion pumps that use pharmacokinetic and pharmacodynamic mathematical modeling to maintain a user-designated target concentration at an effect site typically the brain
The clinician enters a desired target concentration for an anesthetic or another agent The computer calculates the amount of the agent required to achieve the target concentration at the effect site and directs an infusion pump to deliver the calculated boluses or infusions Therefore TIVA-TCI allows a more stable hemodynamic profile during surgery prevents long-acting opioid-induced accumulation and allows rapid recovery from general anesthesia
Total intravenous anaesthesia TIVA regimen with Propofol is a useful anaesthetic technique effectively controlling responses to tracheal intubation and intense surgical stimulation while avoiding Inhalational anaesthetics and allowing rapid emergence from anaesthesia
The clinician enters a desired target concentration for an anesthetic or another agent The computer calculates the amount of the agent required to achieve the target concentration at the effect site and directs an infusion pump to deliver the calculated boluses or infusions Therefore TIVA-TCI allows a more stable hemodynamic profile during surgery prevents long-acting opioid-induced accumulation and allows rapid recovery from general anesthesia
Total intravenous anaesthesia TIVA regimen with Propofol is a useful anaesthetic technique effectively controlling responses to tracheal intubation and intense surgical stimulation while avoiding Inhalational anaesthetics and allowing rapid emergence from anaesthesia
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None