Ignite Creation Date:
2024-05-06 @ 7:29 PM
Last Modification Date:
2024-10-26 @ 3:07 PM
Study NCT ID:
NCT06029946
Status:
NOT_YET_RECRUITING
Last Update Posted:
2023-09-08
First Post:
2023-01-23
Brief Title:
B-mode Ultrasound Sono-Elastography and Diffusion-weighted Imaging MRI in Thyroid Nodules
Sponsor:
Assiut University
Organization:
Assiut University
Study Overview
Official Title:
Comparative Study of B-mode Ultrasound Sono-Elastography and Diffusion-weighted Imaging MRI in the Characterization of Thyroid Nodules
Status:
NOT_YET_RECRUITING
Status Verified Date:
2023-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To compare the accuracy of the conventional Ultrasound TI-RADS US elastography DWI MRI and its ADC value in characterization and differentiation of thyroid nodules
Detailed Description:
Thyroid nodules are one of the most common endocrine carcinomata 1 Most thyroid tumors have a good prognosis if early diagnosis and timely treated 2 An Ultrasound US exam is a safe non-invasive imaging technique for detecting thyroid nodules 3 However still there are no dependable criteria to discriminate malignant from benign lesions 4 In 2009 Horvath et al proposed the Thyroid Imaging Report and Data System TI-RADS The new version of TI-RADS was launched by ACR in 2017 5 Color Doppler ultrasound is also used to differentiate benign from malignant thyroid nodules The presence of intra-nodular vascularity Type 1b was considered close to be malignant 6 US elastography is a novel tool to increase the diagnostic value of Ultrasound and as an adjuvant tool 7 Shear wave elastography evaluates elasticity through the propagation speed of shear waves with the wave speed being faster in hard tissue 8 Conventional T1-and T2-weighted MR imaging can-not differentiate benign from malignant nodules 9 Diffusion-weighted imaging DWI is a non-invasive tool used to distinguish benign from malignant nodules 10 Malignant thyroid nodules usually have a lower ADC value attributed to cellular density and tissue perfusion 11 Combining subjective MRI features with a quantitative measurement could improve the diagnostic yield of DW-MRI 12 The cytological examination by fine-needle aspiration FNA has become a reliable tool to diagnose thyroid cancers 2 Suspicious cytological findings reach up to 30 of all aspirated nodules suggesting the need for less invasive methods 13
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None