Ignite Creation Date:
2025-12-24 @ 7:18 PM
Ignite Modification Date:
2025-12-29 @ 1:42 PM
Study NCT ID:
NCT04434703
Status:
UNKNOWN
Last Update Posted:
2021-01-29
First Post:
2020-06-13
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF)
Sponsor:
Cairo University
Organization:
Study Overview
Official Title:
Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF) A Randomized Clinical Trail :Comparative Study
Status:
UNKNOWN
Status Verified Date:
2021-01
Last Known Status:
ENROLLING_BY_INVITATION
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
the aim of this study is clinically and radiographically evaluate the use of advance platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction
Detailed Description:
systemically healthy patients who have at least one non-restorable tooth in the upper inter-bicuspid region and are not seeking immediate or early implant treatment will be allocated in this study after performing nonsurgical periodontal therapy and preoperative periapical therapy to evaluate and improve the condition of the periodontal tissues.
Anesthesia will be given then flapless atraumatic extraction using periotomes followed by forceps after luxation. For all groups, the socket will be debrided using curette then
* group A, the socket will be filled with A.PRF
* group B the socket will be filled with PRF.
* group C no bio-additive will be added.
* Criss cross horizontal mattress suture will be applied to close the extraction wound.
PRF and A-PRF preparation :
10 ml of blood will be drawn from each patient by vein puncture of the antecubital vein.
* Plateletr ich fibrin (PRF) is 3000 rpm and 10 minutes without addition of anticoagulant
* Advanced platelet rich fibrin (A-PRF) is 1300 rpm and 8 minutes.
Anesthesia will be given then flapless atraumatic extraction using periotomes followed by forceps after luxation. For all groups, the socket will be debrided using curette then
* group A, the socket will be filled with A.PRF
* group B the socket will be filled with PRF.
* group C no bio-additive will be added.
* Criss cross horizontal mattress suture will be applied to close the extraction wound.
PRF and A-PRF preparation :
10 ml of blood will be drawn from each patient by vein puncture of the antecubital vein.
* Plateletr ich fibrin (PRF) is 3000 rpm and 10 minutes without addition of anticoagulant
* Advanced platelet rich fibrin (A-PRF) is 1300 rpm and 8 minutes.
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: