Ignite Creation Date:
2024-05-06 @ 7:28 PM
Last Modification Date:
2024-10-26 @ 3:07 PM
Study NCT ID:
NCT06026436
Status:
RECRUITING
Last Update Posted:
2023-10-27
First Post:
2023-08-30
Brief Title:
Evaluation of the Effectiveness of Platelet-based and Microvesicle-based Assays to Predict Thrombotic and Bleeding Risk in Chronic Kidney Disease Patients With Acute Coronary Syndrome
Sponsor:
Assistance Publique Hopitaux De Marseille
Organization:
Assistance Publique Hopitaux De Marseille
Study Overview
Official Title:
Evaluation of the Effectiveness of Platelet-based and Microvesicle-based Assays to Predict Thrombotic and Bleeding Risk in Chronic Kidney Disease Patients With Acute Coronary Syndrome
Status:
RECRUITING
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
INNOV CKD 1
Brief Summary:
This study is part of the RHU INNOV-CKD winner of the 2019 call for projects Its aim is to develop two biomarker assays to assess the thrombotic and haemorrhagic risks in patients with stage 3A or more severe chronic kidney disease CKD treated with percutaneous coronary intervention PCI and antiplatelet therapy following an acute coronary syndrome ACS We believe that these tests will help to adapt antiplatelet therapy on an individual basis in terms of intensity and duration of treatment and thus reduce the risk of thrombotic and haemorrhagic events in this particularly fragile population The first biomarker corresponds to an intra-platelet molecule Rap1b in its active form known as aRap1b The second is the pro-antithrombotic balance of circulating endothelial microvesicles patEMV which reflects endothelial dysfunction An automated method for measuring these biomarkers will be developed in partnership with the DStago and BioCytex industries during the course of the project
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None