Ignite Creation Date:
2024-05-06 @ 7:28 PM
Last Modification Date:
2024-10-26 @ 3:07 PM
Study NCT ID:
NCT06023134
Status:
ACTIVE_NOT_RECRUITING
Last Update Posted:
2023-09-05
First Post:
2023-08-29
Brief Title:
Clinical Characteristics and Outcomes of Patients With Pulmonary Hypertension Associated Right Heart Failure
Sponsor:
Jingyi Ren
Organization:
China-Japan Friendship Hospital
Study Overview
Official Title:
Clinical Characteristics and Outcomes of Patients With Pulmonary Hypertension Associated Right Heart Failure
Status:
ACTIVE_NOT_RECRUITING
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study aims to describe the clinical characteristics and clarify the predictors of the short- and long-term outcomes of RHF patients further assist the diagnosis risk stratification and treatment of RHF
Detailed Description:
Right heart failureRHF is a clinical syndrome with symptoms signs and evidence of right ventricular systolic andor diastolic dysfunction For many years it was largely neglected in the consideration of left-sided heart failure while it is now evident that RHF is not only common but its presence also strongly contributes to increased morbidity and mortality The in-hospital mortality of RHF is 7 and the 30-day readmission rate is 20 Therefore diagnosis potential treatment strategies and prognosis improvement have become an unmet need in the field of cardiovascular disease
In clinical practice accurate diagnosis of RHF is the key to timely initiation of treatment and improvement of prognosis Although current guidelines recommend clinical symptoms and signs combined with echocardiography cardiac magnetic resonance and other imaging means to evaluate right heart dysfunction for comprehensive diagnosis of right heart failure the key diagnostic indicators included are inconsistent the weight ratio of each indicator is different the diagnostic threshold is not uniform and the lack of comprehensive diagnostic model system brings great challenges to clinical practice
This study aims to integrate multiple clinical biomarkers imaging and hemodynamic data to describe the clinical characteristics establish noninvasive easy-to-use diagnosis models for right heart failure and explore the risk factors for short- and long-term poor prognosis in patients with RHF
In clinical practice accurate diagnosis of RHF is the key to timely initiation of treatment and improvement of prognosis Although current guidelines recommend clinical symptoms and signs combined with echocardiography cardiac magnetic resonance and other imaging means to evaluate right heart dysfunction for comprehensive diagnosis of right heart failure the key diagnostic indicators included are inconsistent the weight ratio of each indicator is different the diagnostic threshold is not uniform and the lack of comprehensive diagnostic model system brings great challenges to clinical practice
This study aims to integrate multiple clinical biomarkers imaging and hemodynamic data to describe the clinical characteristics establish noninvasive easy-to-use diagnosis models for right heart failure and explore the risk factors for short- and long-term poor prognosis in patients with RHF
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None