Ignite Creation Date:
2024-05-06 @ 7:27 PM
Last Modification Date:
2024-10-26 @ 3:07 PM
Study NCT ID:
NCT06016075
Status:
RECRUITING
Last Update Posted:
2023-10-25
First Post:
2023-08-23
Brief Title:
Investigation of Differential Biology of Benign and Malignant Renal Masses Using Advanced Magnetic Resonance Imaging Techniques
Sponsor:
University of Cambridge
Organization:
University of Cambridge
Study Overview
Official Title:
Investigation of Differential Biology of Benign and Malignant Renal Masses Using Advanced Magnetic Resonance Imaging Techniques
Status:
RECRUITING
Status Verified Date:
2023-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
IBM-Renal
Brief Summary:
The aim of this study is to develop techniques for non-invasive imaging of biology in participants with benign or malignant renal masses based on the novel scanning MRI techniques including recently invented Hyperpolarised MRI deuterium metabolic imaging and sodium MRI This imaging study will 1 acquire imaging data from human tissues following the injection of hyperpolarised 13C pyruvate and use 13C-MRI to monitor changes in the ratio of 13C-lactate to 13C-pyruvate 2 acquire imaging data from human tissues using Sodium MRI or 3 acquire imaging data from human tissues following the oral consumable of deuterated glucose Data acquired during this physiological study will be used to optimise future imaging protocolsIn the UK and possibly in other countries there are some patients with renal masses that are over treated or undergo unnecessary procedures such as surgery or biopsies as they are thought to have a malignant tumour or a more aggressive tumour but after the procedure it is found that the mass was benign The aim of this study is to determine whether one or all of these imaging techniques can differentiate between benign and malignant renal masses with the view to developing the techniques further and hopefully reducing the need for over treatment or unnecessary procedures in patients with benign masses
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 314155 | REGISTRY | Integrated Research Application System | None |
| 22EE0136 | REGISTRY | None | None |