Ignite Creation Date:
2024-05-06 @ 7:26 PM
Last Modification Date:
2024-10-26 @ 3:07 PM
Study NCT ID:
NCT06017037
Status:
RECRUITING
Last Update Posted:
2023-08-30
First Post:
2023-05-15
Brief Title:
REward Processing And Citalopram Study
Sponsor:
University of Oxford
Organization:
University of Oxford
Study Overview
Official Title:
REward Processing And Citalopram Study
Status:
RECRUITING
Status Verified Date:
2023-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
REPAC
Brief Summary:
The goal of this experimental medicine study is to examine the effect of increasing serotonin on reward processing in healthy volunteers The main questions it aims to answer are
1 Does a subacute increase in serotonin influence the activation regions during reward learning
2 Does a subacute increase in serotonin influence behavioural markers of reward valuation effort task responsiveness taste task and learning learning task
Participants will be
given a 7-day course of the selective serotonin reuptake inhibitor citalopram undergo behavioural testing complete a reward learning task whilst undergoing fMRI
Researchers will compare results against a placebo group
1 Does a subacute increase in serotonin influence the activation regions during reward learning
2 Does a subacute increase in serotonin influence behavioural markers of reward valuation effort task responsiveness taste task and learning learning task
Participants will be
given a 7-day course of the selective serotonin reuptake inhibitor citalopram undergo behavioural testing complete a reward learning task whilst undergoing fMRI
Researchers will compare results against a placebo group
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None