Ignite Creation Date:
2024-05-06 @ 7:25 PM
Last Modification Date:
2024-10-26 @ 3:06 PM
Study NCT ID:
NCT06005480
Status:
COMPLETED
Last Update Posted:
2024-06-17
First Post:
2023-07-16
Brief Title:
Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers
Sponsor:
Brigham and Womens Hospital
Organization:
Brigham and Womens Hospital
Study Overview
Official Title:
Understanding Rebound Pain After Regional Anesthesia Resolution Mechanistic Trial in Healthy Volunteers
Status:
COMPLETED
Status Verified Date:
2024-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Regional anesthesia decreases postoperative pain scores and opioid consumption and may prevent chronic pain after surgery in patients undergoing surgery However some patients experience an increase of pain into the severe range when the nerve block wears off also known as rebound pain The investigators are studying if a nerve block numbing injection in the arm causes hyperalgesia increased pain when the nerve block is wearing off
Detailed Description:
This is a prospective randomized study in healthy volunteers who will undergo sensory testing using quantitative sensory testing QST complete psychosocial and pain questionnaires and ultrasound-guided peripheral nerve block of the arm axillary nerve block in a supervised monitored setting BWH Clinical Investigation Center The investigators plan to assess the association between different QST modalities at different time points pre- and post-nerve block resolution Semi-structured interviews and qualitative analysis will be used to explore patients experiences with nerve block placement
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None