Ignite Creation Date:
2024-05-06 @ 7:25 PM
Last Modification Date:
2024-10-26 @ 3:06 PM
Study NCT ID:
NCT06000176
Status:
COMPLETED
Last Update Posted:
2023-08-21
First Post:
2023-08-12
Brief Title:
Comparison of Optical Coherence Tomography Angiography Microvascular Changes in Primary Open Angle and Primary Angle Closure Glaucoma
Sponsor:
Omar Said
Organization:
Fayoum University
Study Overview
Official Title:
Comparison of Optical Coherence Tomography Angiography Microvascular Changes in Primary Open Angle and Primary Angle Closure Glaucoma
Status:
COMPLETED
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This work aims to study the peripapillary and macular microvascular changes in primary open angle and primary angle closure glaucoma using Optical Coherence Tomography Angiography OCTA
Detailed Description:
After approval of the local institutional ethics committee and local institutional review board all patients presenting to the outpatient clinic of the department of Ophthalmology in the universities has been subjected to routine ophthalmological examination including best corrected visual acuity BCVA Slit-lamp evaluation of anterior segment IOP by Goldmann applanation tonometer Gonioscopy using gonio contact lens Fundus examination by indirect opthalmoscope with history taking focusing on positive family history of glaucoma after a detailed informed consent was signed by eligible patients and investigated by OCTA of the Peripapillary and Macular vascular density on presentation using AngiVue Optovue Inc Fremont CA USA
Data analysis performed using the Statistical Package of Social Science SPSS software version 22 in windows 7 SPSS Inc Chicago IL USA Simple descriptive statistical analysis in the form of numbers and percentages of qualitative data and arithmetic means as central tendency measurement standard deviations as a measure of dispersion of quantitative parametric data
For quantitative parametric data Independent samples test was used to compare quantitative measures between two independent groups One-way analysis of variance ANOVA test used to compare quantitative measures between more than two independent groups of quantitative data with the benferroni Post-HOC to test the significance between each two groups Paired t-test used to compare two dependent quantitative data
For qualitative data Chi square test used to compare between two or more than two qualitative groups
Bivariate Pearson correlation test to test the association between variables The probability value P-value 005 was considered as statistical significant
Data analysis performed using the Statistical Package of Social Science SPSS software version 22 in windows 7 SPSS Inc Chicago IL USA Simple descriptive statistical analysis in the form of numbers and percentages of qualitative data and arithmetic means as central tendency measurement standard deviations as a measure of dispersion of quantitative parametric data
For quantitative parametric data Independent samples test was used to compare quantitative measures between two independent groups One-way analysis of variance ANOVA test used to compare quantitative measures between more than two independent groups of quantitative data with the benferroni Post-HOC to test the significance between each two groups Paired t-test used to compare two dependent quantitative data
For qualitative data Chi square test used to compare between two or more than two qualitative groups
Bivariate Pearson correlation test to test the association between variables The probability value P-value 005 was considered as statistical significant
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None