Ignite Creation Date:
2024-05-06 @ 7:23 PM
Last Modification Date:
2024-10-26 @ 3:06 PM
Study NCT ID:
NCT05996276
Status:
RECRUITING
Last Update Posted:
2023-08-18
First Post:
2023-08-01
Brief Title:
Impact of Dose to Cardiac Substructures on Survival in Patients With Esophageal Cancer Treated With Radiotherapy or Chemoradiotherapy SATIATION
Sponsor:
University Hospital Brest
Organization:
University Hospital Brest
Study Overview
Official Title:
Impact of Dose to Cardiac Substructures on Survival in Patients With Esophageal Cancer Treated With Radiotherapy or Chemoradiotherapy
Status:
RECRUITING
Status Verified Date:
2023-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SATIATION
Brief Summary:
Treatment of non-operable esophageal cancers is based on radiochemotherapy or exclusive radiotherapy
The cardiac toxicity of radiotherapy in the treatment of thoracic tumor localizations is well documented however more and more studies are calling for the use of dosimetric parameters related to cardiac sub-structures to be integrated into clinical practice rather than considering the heart as a whole
With this in mind the aim of this study is to define the parameters particularly dosimetric ones linked to cardiac sub-structures influencing survival in patients treated with exclusive radiotherapy or radiochemotherapy for esophageal cancer
The cardiac toxicity of radiotherapy in the treatment of thoracic tumor localizations is well documented however more and more studies are calling for the use of dosimetric parameters related to cardiac sub-structures to be integrated into clinical practice rather than considering the heart as a whole
With this in mind the aim of this study is to define the parameters particularly dosimetric ones linked to cardiac sub-structures influencing survival in patients treated with exclusive radiotherapy or radiochemotherapy for esophageal cancer
Detailed Description:
Treatment of non-operable esophageal cancers is based on radiochemotherapy or exclusive radiotherapy
The cardiac toxicity of radiotherapy in the treatment of thoracic tumor localizations is well documented however more and more studies are calling for the use of dosimetric parameters related to cardiac sub-structures to be integrated into clinical practice rather than considering the heart as a whole
Although most of these data have been studied in populations with long-term follow-up such as breast cancer cardiac toxicity and the reduced survival it entails are also found in diseases such as esophageal cancer
With this in mind the aim of this study is to define the parameters particularly dosimetric ones linked to cardiac sub-structures influencing survival in patients treated with exclusive radiotherapy or radiochemotherapy for esophageal cancer
The cardiac toxicity of radiotherapy in the treatment of thoracic tumor localizations is well documented however more and more studies are calling for the use of dosimetric parameters related to cardiac sub-structures to be integrated into clinical practice rather than considering the heart as a whole
Although most of these data have been studied in populations with long-term follow-up such as breast cancer cardiac toxicity and the reduced survival it entails are also found in diseases such as esophageal cancer
With this in mind the aim of this study is to define the parameters particularly dosimetric ones linked to cardiac sub-structures influencing survival in patients treated with exclusive radiotherapy or radiochemotherapy for esophageal cancer
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None