Ignite Creation Date:
2024-05-06 @ 7:23 PM
Last Modification Date:
2024-10-26 @ 3:06 PM
Study NCT ID:
NCT05994014
Status:
RECRUITING
Last Update Posted:
2023-08-16
First Post:
2023-08-08
Brief Title:
PETCT vs Cardiac CT for Detecting Coronary Atherosclerotic Disease PET Positron Emission Tomography CT Computed Tomography
Sponsor:
Johns Hopkins University
Organization:
Johns Hopkins University
Study Overview
Official Title:
PETCT vs Cardiac CT for Detecting Coronary Atherosclerotic Disease
Status:
RECRUITING
Status Verified Date:
2024-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PET CT
Brief Summary:
Early detection of coronary atherosclerotic disease facilitates adequate prevention The purpose of this study is to compare an assessment of coronary atherosclerotic disease burden by positron emission tomography computed tomography NaF-PETCT with those of conventional and ultra-high-resolution-CT UHR-CT in patients with suspected coronary artery disease For this purpose the investigators plan to include 33 patients with symptoms concerning for CAD who have been referred for cardiac CT testing
Detailed Description:
Early detection of coronary atherosclerotic disease facilitates adequate prevention 18 Fluoride F -sodium fluoride PETCT NaF-PET CT has been shown to detect aortic microcalcification as early manifestation of atherosclerosis in experimental and early clinical investigations The capability of NaF-PETCT to detect coronary atherosclerotic disease in humans remains unclear Given its sensitivity to detect vascular microcalcification undetectable by conventional CT NaF-PETCT may be an attractive noninvasive test for early detection of coronary atherosclerosis
The purpose of this study is to compare an assessment of coronary atherosclerotic disease burden by positron emission tomography computed tomography NaF-PETCT with those of conventional and ultra-high-resolution-CT UHR-CT in patients with suspected coronary artery disease CAD For this purpose the investigators plan to include 33 patients with symptoms concerning for CAD who have been referred for cardiac CT testing In addition to the clinically indicated and performed cardiac CT scan participants will be asked to also undergo NaF-PETCT for comparison of atherosclerosis assessment among the two tests single center prospective diagnostic accuracy study
The purpose of this study is to compare an assessment of coronary atherosclerotic disease burden by positron emission tomography computed tomography NaF-PETCT with those of conventional and ultra-high-resolution-CT UHR-CT in patients with suspected coronary artery disease CAD For this purpose the investigators plan to include 33 patients with symptoms concerning for CAD who have been referred for cardiac CT testing In addition to the clinically indicated and performed cardiac CT scan participants will be asked to also undergo NaF-PETCT for comparison of atherosclerosis assessment among the two tests single center prospective diagnostic accuracy study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
True
Is an FDA AA801 Violation?:
None